Weber Lara Smith - 12 Jan 2026 Form 4 Insider Report for FRACTYL HEALTH, INC. (GUTS)

Role: Chief Financial Officer
Signature: /s/ Sarah Toomey, Attorney-in-Fact
Issuer symbol: GUTS
Transactions as of: 12 Jan 2026
Net transactions value: $0
Form type: 4
Filing time: 14 Jan 2026, 16:30:03 UTC
SEC: View on sec.gov

Reporting Owners (1)

Name	Relationship	Address	Signature	Signature date	CIK
Smith Weber Lara	Chief Financial Officer	3 VAN DE GRAAFF DRIVE SUITE 200, BURLINGTON	/s/ Sarah Toomey, Attorney-in-Fact	14 Jan 2026	0002105051

Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Underlying Class	Amount	Exercise Price	Ownership	Footnotes
transaction	GUTS	Stock Option	Award	$0	+1,036,800		$0.000000	1,036,800	12 Jan 2026	Common Stock	1,036,800	$2.00	Direct	F1

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id	Content
F1	The stock option vests and becomes exercisable as to 25% of the shares subject to the option on January 12, 2027, with the remaining 75% of the underlying shares vesting in 36 equal monthly installments thereafter, subject to the Reporting Person's continuous service with the Company as of each such vesting date.