Brian N. Cherry - 12 Jan 2026 Form 4 Insider Report for Zymeworks Inc. (ZYME)

Role: Director
Signature: /s/ Daniel Dex, Attorney-in-Fact
Issuer symbol: ZYME
Transactions as of: 12 Jan 2026
Net transactions value: $0
Form type: 4
Filing time: 13 Jan 2026, 16:30:03 UTC
SEC: View on sec.gov

Reporting Owners (1)

Name	Relationship	Address	Signature	Signature date	CIK
Cherry Brian N	Director	C/O ZYMEWORKS INC., 108 PATRIOT DRIVE, SUITE A, MIDDLETOWN	/s/ Daniel Dex, Attorney-in-Fact	13 Jan 2026	0001290922

Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Underlying Class	Amount	Exercise Price	Ownership	Footnotes
transaction	ZYME	Stock Option (Right to Buy)	Award	$0	+23,000		$0.000000	23,000	12 Jan 2026	Common Stock	23,000	$23.16	Direct	F1
transaction	ZYME	Restricted Stock Unit	Award	$0	+15,400		$0.000000	15,400	12 Jan 2026	Common Stock	15,400		Direct	F2, F3

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id	Content
F1	Stock options vest in 36 equal monthly installments starting one month after grant date of January 12, 2026.
F2	Each restricted stock unit ("RSU") represents the contingent right to receive, upon vesting of the RSU, one share of common stock.
F3	RSUs vest in three equal annual installments beginning on first anniversary of grant date.