LEONE D. PATTERSON - 06 Jan 2026 Form 4 Insider Report for Zymeworks Inc. (ZYME)

Role: EVP, Chief Bus & Fin Officer
Signature: /s/ Daniel Dex, Attorney-in-Fact
Issuer symbol: ZYME
Transactions as of: 06 Jan 2026
Net transactions value: +$4,842
Form type: 4
Filing time: 07 Jan 2026, 19:37:56 UTC
Previous filing: 09 Jun 2025
SEC: View on sec.gov

Reporting Owners (1)

Name	Relationship	Address	Signature	Signature date	CIK
PATTERSON LEONE D	EVP, Chief Bus & Fin Officer	C/O ZYMEWORKS INC., 108 PATRIOT DRIVE, SUITE A, MIDDLETOWN	/s/ Daniel Dex, Attorney-in-Fact	07 Jan 2026	0001233539

Transactions Table

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Ownership	Footnotes
transaction	ZYME	Common Stock	Award	$4,842	+459		$10.55	459	06 Jan 2026	Direct	F1

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id	Content
F1	Shares of common stock purchased pursuant to the Issuer's Amended and Restated Employee Stock Purchase Plan (ESPP) for the ESPP purchase period July 1, 2025 through December 31, 2025. In accordance with the ESPP, the shares of common stock were purchased at a price equal to 85% of the closing price of the Issuer's common stock on July 1, 2025.