Karen Marie Walker - 15 Dec 2025 Form 4 Insider Report for Kyverna Therapeutics, Inc. (KYTX)

Signature
/s/ Samantha Eldredge, as Attorney-in-Fact
Issuer symbol
KYTX
Transactions as of
15 Dec 2025
Net transactions value
-$176,865
Form type
4
Filing time
17 Dec 2025, 20:30:03 UTC
Previous filing
15 Apr 2025

Reporting Owners (1)

Name Relationship Address Signature Signature date CIK
Walker Karen Marie Chief Technology Officer C/O KYVERNA THERAPEUTICS, INC., 5980 HORTON ST., STE 550, EMERYVILLE /s/ Samantha Eldredge, as Attorney-in-Fact 17 Dec 2025 0002008556

Transactions Table

Type Sym Class Transaction Value $ Shares Change % * Price $ Shares After Date Ownership Footnotes
transaction KYTX Common Stock Options Exercise $115,910 +23,998 +106% $4.83 46,634 15 Dec 2025 Direct F1
transaction KYTX Common Stock Sale $292,776 -23,998 -51% $12.20 22,636 15 Dec 2025 Direct F1

Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)

Type Sym Class Transaction Value $ Shares Change % * Price $ Shares After Date Underlying Class Amount Exercise Price Ownership Footnotes
transaction KYTX Stock option (right to buy) Options Exercise $0 -23,998 -22% $0.000000 85,865 15 Dec 2025 Common Stock 23,998 $4.83 Direct F1, F2
* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Buy Plan / Sale Plan: These are also open market purchases/sales of shares, but in this case the transaction is part of a trading plan. Rule 10b5-1 allows insiders to setup a trading plan to buy/sell stocks over a certain period of time. Since the purchases/sales are predetermined, this protects the insiders from violating insider trading law.

Transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c).

Explanation of Responses:

Id Content
F1 The transactions reported in this Form 4 were made pursuant to a Rule 10b5-1 plan adopted by the Reporting Person on September 12, 2025 in effect at the time of such transactions.
F2 25% of the original number of shares subject to the option vested on January 1, 2025, and 1/48th of the original number of shares subject to the option vests in monthly installments thereafter, subject to the Reporting Person's continuous service.