John D. Quisel - 11 Dec 2025 Form 4 Insider Report for Disc Medicine, Inc. (IRON)

Role
Chief Executive Officer, Director
Signature
By: /s/ Rahul Khara, as Attorney-in-Fact
Issuer symbol
IRON
Transactions as of
11 Dec 2025
Transactions value $
-$3,327,531
Form type
4
Filing time
15 Dec 2025, 17:49:00 UTC
Previous filing
11 Sep 2025
SEC
View on sec.gov

Reporting Owners (1)

Name Relationship Address Signature Signature date CIK
Quisel John D Chief Executive Officer, Director C/O DISC MEDICINE, INC., 321 ARSENAL STREET, SUITE 101, WATERTOWN By: /s/ Rahul Khara, as Attorney-in-Fact 15 Dec 2025 0001586788

Transactions Table

Type Sym Class Transaction Value $ Shares Change % * Price $ Shares After Date Ownership Footnotes
transaction IRON Common Stock Options Exercise $394K +40K +23.28% $9.86 212K 11 Dec 2025 Direct F1
transaction IRON Common Stock Sale -$220K -2.42K -1.14% $90.97 209K 11 Dec 2025 Direct F1, F2
transaction IRON Common Stock Sale -$400K -4.34K -2.07% $92.21 205K 11 Dec 2025 Direct F1, F3
transaction IRON Common Stock Sale -$1.52M -16.4K -7.98% $92.96 189K 11 Dec 2025 Direct F1, F4
transaction IRON Common Stock Sale -$1.58M -16.9K -8.95% $93.65 172K 11 Dec 2025 Direct F1, F5

Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)

Type Sym Class Transaction Value $ Shares Change % * Price $ Shares After Date Underlying Class Amount Exercise Price Ownership Footnotes
transaction IRON Stock Option (Right to Buy) Options Exercise $0 -40K -34.67% $0.00 75.4K 11 Dec 2025 Common Stock 40K $9.86 Direct F1, F6
* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Buy Plan / Sale Plan: These are also open market purchases/sales of shares, but in this case the transaction is part of a trading plan. Rule 10b5-1 allows insiders to setup a trading plan to buy/sell stocks over a certain period of time. Since the purchases/sales are predetermined, this protects the insiders from violating insider trading law.

Transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c).

Explanation of Responses:

Id Content
F1 The transactions reported by the Reporting Person were effected pursuant to a Rule 10b5-1 trading plan adopted on February 13, 2025.
F2 The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $90.40 to $91.37, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnotes (2) through (5) to this Form 4.
F3 The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $91.46 to $92.43, inclusive.
F4 The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $92.46 to $93.44, inclusive.
F5 The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $93.46 to $94.24, inclusive.
F6 The shares underlying this option are fully vested and exercisable as of the date hereof.