| Name | Relationship | Address | Signature | Signature date | CIK |
|---|---|---|---|---|---|
| Erdtmann Rainer M | President, Chief Operating Officer, Principal Financial Officer, and Principal Accounting Officer, Director | C/O BIOMEA FUSION, INC., 1599 INDUSTRIAL ROAD, SAN CARLOS | /s/ Rainer M. Erdtmann | 15 Dec 2025 | 0001455767 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | BMEA | Common Stock | Purchase | $42,999 | +30,000 | +4.3% | $1.43 | 723,027 | 11 Dec 2025 | Direct | F1 |
| holding | BMEA | Common Stock | 19,400 | 11 Dec 2025 | By daughter | ||||||
| holding | BMEA | Common Stock | 20,000 | 11 Dec 2025 | By son | ||||||
| holding | BMEA | Common Stock | 20,000 | 11 Dec 2025 | By daughter | ||||||
| holding | BMEA | Common Stock | 174,614 | 11 Dec 2025 | See Footnote | F2 | |||||
| holding | BMEA | Common Stock | 1,134,989 | 11 Dec 2025 | See Footnote | F3 | |||||
| holding | BMEA | Common Stock | 228,470 | 11 Dec 2025 | See Footnote | F4 | |||||
| holding | BMEA | Common Stock | 252,320 | 11 Dec 2025 | See Footnote | F5 |
| Id | Content |
|---|---|
| F1 | The price reported in Column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $1.42 to $1.46, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares purchased at each separate price within the range. |
| F2 | The shares are held by a trust having an independent trustee ("Trust 1"). The Reporting Person disclaims Section 16 beneficial ownership of the securities, except to the extent of his pecuniary interest therein, if any, and this report shall not be deemed to be an admission that he has beneficial ownership of such shares for Section 16 or any other purpose. |
| F3 | The shares are held by a trust having an independent trustee ("Trust 2"). The Reporting Person disclaims Section 16 beneficial ownership of the securities, except to the extent of his pecuniary interest therein, if any, and this report shall not be deemed to be an admission that he has beneficial ownership of such shares for Section 16 or any other purpose. |
| F4 | The shares are held directly by Point Sur Investors Fund I, LP ("Point Sur LP"). The General Partner of Point Sur LP is Point Sur Investors LLC. The Reporting Person is a managing member of Point Sur Investors, LLC and as such has voting and dispositive power over the securities held by Point Sur LP. The Reporting Person disclaims Section 16 beneficial ownership of the securities, except to the extent of his pecuniary interest therein, if any, and this report shall not be deemed to be an admission that he has beneficial ownership of such shares for Section 16 or any other purpose. |
| F5 | The shares are held directly by Point Sur Investors, LLC. The Reporting Person is a managing members of Point Sur Investors, LLC and as such has voting and dispositive power over the securities held by Point Sur Investors, LLC. The Reporting Person disclaims Section 16 beneficial ownership of the securities, except to the extent of his pecuniary interest therein, if any, and this report shall not be deemed to be an admission that he has beneficial ownership of such shares for Section 16 or any other purpose. |
President, Chief Operating Officer, Principal Financial Officer, and Principal Accounting Officer