Graham G. Walmsley - Oct 8, 2025 Form 4 Insider Report for Akero Therapeutics, Inc. (AKRO)

Role: Director
Signature: /s/ Jonathan Young, Attorney-in-Fact
Stock symbol: AKRO
Transactions as of: Oct 8, 2025
Transactions value $: $1,866,155
Form type: 4
Date filed: 10/10/2025, 07:48 PM
Previous filing: Jun 13, 2025
SEC: View on sec.gov

Reporting Owners (1)

Name	Relationship	Address	Signature	Signature date	CIK
Graham G. Walmsley	Director	601 GATEWAY BOULEVARD, SUITE 350, SOUTH SAN FRANCISCO	/s/ Jonathan Young, Attorney-in-Fact	2025-10-10	0001777517

Transactions Table

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Ownership	Footnotes
transaction	AKRO	Common Stock	Options Exercise	$599K	+26K	+1199.26%	$23.02	28.2K	Oct 8, 2025	Direct
transaction	AKRO	Common Stock	Options Exercise	$122K	+15K	+53.25%	$8.13	43.2K	Oct 8, 2025	Direct
transaction	AKRO	Common Stock	Options Exercise	$342K	+13K	+30.11%	$26.32	56.2K	Oct 8, 2025	Direct
transaction	AKRO	Common Stock	Options Exercise	$328K	+13K	+23.14%	$25.20	69.2K	Oct 8, 2025	Direct
transaction	AKRO	Common Stock	Options Exercise	$476K	+23.8K	+34.46%	$19.97	93K	Oct 8, 2025	Direct
holding	AKRO	Common Stock						1.2M	Oct 8, 2025	See Footnote	F1

Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Date	Underlying Class	Amount	Exercise Price	Ownership	Footnotes
transaction	AKRO	Stock Option (Right to Buy)	Options Exercise	$0	-26K	-100%	$0.00	Oct 8, 2025	Common Stock	26K	$23.02	Direct	F2
transaction	AKRO	Stock Option (Right to Buy)	Options Exercise	$0	-15K	-100%	$0.00	Oct 8, 2025	Common Stock	15K	$8.13	Direct	F2
transaction	AKRO	Stock Option (Right to Buy)	Options Exercise	$0	-13K	-100%	$0.00	Oct 8, 2025	Common Stock	13K	$26.32	Direct	F2
transaction	AKRO	Stock Option (Right to Buy)	Options Exercise	$0	-13K	-100%	$0.00	Oct 8, 2025	Common Stock	13K	$25.20	Direct	F2
transaction	AKRO	Stock Option (Right to Buy)	Options Exercise	$0	-23.8K	-100%	$0.00	Oct 8, 2025	Common Stock	23.8K	$19.97	Direct	F2

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id	Content
F1	The shares are held by Logos Global Master Fund LP ("Logos Master Fund") and Logos Opportunities Fund IV LP ("LOF IV"). Logos GP LLC ("Logos GP") is the general partner of Logos Master Fund and the Reporting Person is a managing member of Logos GP. Logos Opportunities IV GP LLC ("GP IV") is the general partner of LOF IV and the Reporting Person is a managing member of GP IV. The Reporting Person disclaims beneficial ownership of the securities except to the extent of his pecuniary interest therein.
F2	The options are vested and currently exercisable.

Content

The shares are held by Logos Global Master Fund LP ("Logos Master Fund") and Logos Opportunities Fund IV LP ("LOF IV"). Logos GP LLC ("Logos GP") is the general partner of Logos Master Fund and the Reporting Person is a managing member of Logos GP. Logos Opportunities IV GP LLC ("GP IV") is the general partner of LOF IV and the Reporting Person is a managing member of GP IV. The Reporting Person disclaims beneficial ownership of the securities except to the extent of his pecuniary interest therein.

The options are vested and currently exercisable.