Eran Ophir - 18 Mar 2026 Form 3 Insider Report for COMPUGEN LTD (CGEN)

Role: President and CEO, Director
Signature: /s/ Eran Ophir
Issuer symbol: CGEN
Transactions as of: 18 Mar 2026
Net transactions value: $0
Form type: 3
Filing time: 18 Mar 2026, 06:19:54 UTC
SEC: View on sec.gov

Reporting Owners (1)

Name	Relationship	Address	Signature	Signature date	CIK
Ophir Eran	President and CEO, Director	C/O COMPUGEN LTD., 26 HAROKMIM STREET, HOLON, ISRAEL	/s/ Eran Ophir	18 Mar 2026	0001972103

Transactions Table

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Ownership	Footnotes
holding	CGEN	Ordinary Shares						11,375	18 Mar 2026	Direct	F1

Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Underlying Class	Amount	Exercise Price	Ownership	Footnotes
holding	CGEN	Share Option (right to buy)							18 Mar 2026	Ordinary Shares	6,750	$6.65	Direct	F2
holding	CGEN	Share Option (right to buy)							18 Mar 2026	Ordinary Shares	3,000	$2.85	Direct	F2
holding	CGEN	Share Option (right to buy)							18 Mar 2026	Ordinary Shares	11,250	$3.15	Direct	F2
holding	CGEN	Share Option (right to buy)							18 Mar 2026	Ordinary Shares	32,000	$3.25	Direct	F2
holding	CGEN	Share Option (right to buy)							18 Mar 2026	Ordinary Shares	50,000	$14.40	Direct	F2
holding	CGEN	Share Option (right to buy)							18 Mar 2026	Ordinary Shares	50,000	$6.45	Direct	F2
holding	CGEN	Share Option (right to buy)							18 Mar 2026	Ordinary Shares	60,000	$3.24	Direct	F3
holding	CGEN	Share Option (right to buy)							18 Mar 2026	Ordinary Shares	30,000	$0.8292	Direct	F4
holding	CGEN	Share Option (right to buy)							18 Mar 2026	Ordinary Shares	65,000	$1.15	Direct	F5
holding	CGEN	Share Option (right to buy)							18 Mar 2026	Ordinary Shares	42,250	$1.69	Direct	F6
holding	CGEN	Share Option (right to buy)							18 Mar 2026	Ordinary Shares	65,000	$1.46	Direct	F7
holding	CGEN	Share Option (right to buy)							18 Mar 2026	Ordinary Shares	135,000	$1.38	Direct	F7

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id	Content
F1	Includes 7,821 restricted stock units ("RSUs"). The RSUs vest in 11 equal quarterly installments commencing on March 31, 2026, subject to the Reporting Person's continued service to the Issuer.
F2	Fully vested.
F3	This option vested 25% on March 31, 2023 and the remainder vested or vests in 12 equal quarterly installments thereafter, subject to the Reporting Person's continued service to the Issuer.
F4	This option vested 25% on December 31, 2023 and the remainder vested or vests in 12 equal quarterly installments thereafter, subject to the Reporting Person's continued service to the Issuer.
F5	This option vested 25% on September 30, 2024 and the remainder vested or vests in 12 equal quarterly installments thereafter, subject to the Reporting Person's continued service to the Issuer.
F6	This option vested 25% on September 30, 2025 and the remainder vested or vests in 12 equal quarterly installments thereafter, subject to the Reporting Person's continued service to the Issuer.
F7	This option vests 25% on September 30, 2026 and the remainder vests in equal 12 quarterly installments thereafter, subject to the Reporting Person's continued service to the Issuer.