Cedric Francois - 14 Jul 2025 Form 4 Insider Report for Apellis Pharmaceuticals, Inc. (APLS)

Signature
/s/ David Watson, attorney-in-fact for Cedric Francois
Issuer symbol
APLS
Transactions as of
14 Jul 2025
Net transactions value
-$2,528,619
Form type
4
Filing time
16 Jul 2025, 16:11:00 UTC
Previous filing
11 Jun 2025
Next filing
18 Jul 2025

Reporting Owners (1)

Name Relationship Address Signature Signature date CIK
Francois Cedric Chief Executive Officer, Director C/O APELLIS PHARMACEUTICALS, INC., 100 FIFTH AVENUE, 3RD FLOOR, WALTHAM /s/ David Watson, attorney-in-fact for Cedric Francois 16 Jul 2025 0001658080

Transactions Table

Type Sym Class Transaction Value $ Shares Change % * Price $ Shares After Date Ownership Footnotes
transaction APLS Common Stock Options Exercise $281,025 +65,203 +16% $4.31 480,898 14 Jul 2025 Direct F1
transaction APLS Common Stock Sale $2,774,923 -137,465 -29% $20.19 343,433 14 Jul 2025 Direct F1, F2
transaction APLS Common Stock Options Exercise $3,448 +800 +0.23% $4.31 344,233 15 Jul 2025 Direct F1
transaction APLS Common Stock Sale $38,168 -1,900 -0.55% $20.09 342,333 15 Jul 2025 Direct F1, F3
holding APLS Common Stock 532,946 14 Jul 2025 Indirect Owner (The Cedric Francois Irrevocable Trust of 2023 - 2) F4
holding APLS Common Stock 472,065 14 Jul 2025 Indirect Owner (The Cedric Francois Irrevocable Trust of 2023) F5
holding APLS Common Stock 300,000 14 Jul 2025 Indirect Owner (The Francois Grossi Trust) F6
holding APLS Common Stock 234,411 14 Jul 2025 Indirect Owner (The Francois-DuBois Educational Trust) F7

Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)

Type Sym Class Transaction Value $ Shares Change % * Price $ Shares After Date Underlying Class Amount Exercise Price Ownership Footnotes
transaction APLS Stock Option (Right to Buy) Options Exercise $0 -65,203 -37% $0.000000 110,335 14 Jul 2025 Common Stock 65,203 $4.31 Direct F1, F8
transaction APLS Stock Option (Right to Buy) Options Exercise $0 -800 -0.73% $0.000000 109,535 15 Jul 2025 Common Stock 800 $4.31 Direct F1, F8
* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Buy Plan / Sale Plan: These are also open market purchases/sales of shares, but in this case the transaction is part of a trading plan. Rule 10b5-1 allows insiders to setup a trading plan to buy/sell stocks over a certain period of time. Since the purchases/sales are predetermined, this protects the insiders from violating insider trading law.

Transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c).

Explanation of Responses:

Id Content
F1 This is a scheduled exercise & sale from 10b5-1 trading plan dated March 10, 2025.
F2 This transaction was executed in multiple trades at prices ranging from $20 - $20.58. The price reported above reflects the weighted average sale price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was affected.
F3 This transaction was executed in multiple trades at prices ranging from $20 - $20.19. The price reported above reflects the weighted average sale price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was affected.
F4 The securities are held by The Cedric Francois Irrevocable Trust of 2023 - 2. William V. A. Zorn is the trustee of The Cedric Francois Irrevocable Trust of 2023 - 2. The reporting person disclaims beneficial ownership over the shares held by The Cedric Francois Irrevocable Trust of 2023 - 2 except to the extent of his pecuniary interest therein.
F5 The securities are held by The Cedric Francois Irrevocable Trust of 2023. William V. A. Zorn is the trustee of The Cedric Francois Irrevocable Trust of 2023. The reporting person disclaims beneficial ownership over the shares held by The Cedric Francois Irrevocable Trust of 2023 except to the extent of his pecuniary interest therein.
F6 The securities are held by The Francois Grossi Trust, for which Juliana Grossi, the spouse of the reporting person, serves as trustee. The reporting person disclaims beneficial ownership over the shares held by the Francois Grossi Trust except to the extent of his pecuniary interest therein.
F7 The securities are held by The Francois-DuBois Educational Trust, for which the Fiduciary Trust Company of New England serves as trustee. The reporting person disclaims beneficial ownership over the shares held by The Francois-DuBois Educational Trust except to the extent of his pecuniary interest therein.
F8 This option was granted on August 21, 2017 and is fully vested.