Martine A. Rothblatt - 13 Mar 2026 Form 4 Insider Report for UNITED THERAPEUTICS Corp (UTHR)

Role: Chairperson & CEO, Director
Signature: /s/ John S. Hess, Jr. under Power of Attorney
Issuer symbol: UTHR
Transactions as of: 13 Mar 2026
Net transactions value: -$5,110,967
Form type: 4
Filing time: 16 Mar 2026, 16:30:53 UTC
Previous filing: 16 Mar 2026
Next filing: 17 Mar 2026
SEC: View on sec.gov

Reporting Owners (1)

Name	Relationship	Address	Signature	Signature date	CIK
ROTHBLATT MARTINE A	Chairperson & CEO, Director	C/O UNITED THERAPEUTICS CORPORATION, 1000 SPRING STREET, SILVER SPRING	/s/ John S. Hess, Jr. under Power of Attorney	16 Mar 2026	0001106578

Transactions Table

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Ownership	Footnotes
transaction	UTHR	Common Stock	Options Exercise		+9,500	+7308%	$146.03^*	9,630	13 Mar 2026	Direct	F1
transaction	UTHR	Common Stock	Sale	$505,443	-944	-9.8%	$535.43	8,686	13 Mar 2026	Direct	F1, F2
transaction	UTHR	Common Stock	Sale	$823,788	-1,536	-18%	$536.32	7,150	13 Mar 2026	Direct	F1, F3
transaction	UTHR	Common Stock	Sale	$1,090,707	-2,030	-28%	$537.29	5,120	13 Mar 2026	Direct	F1, F4
transaction	UTHR	Common Stock	Sale	$1,086,852	-2,019	-39%	$538.31	3,101	13 Mar 2026	Direct	F1, F5
transaction	UTHR	Common Stock	Sale	$833,702	-1,546	-50%	$539.26	1,555	13 Mar 2026	Direct	F1, F6
transaction	UTHR	Common Stock	Sale	$467,333	-865	-56%	$540.27	690	13 Mar 2026	Direct	F1, F7
transaction	UTHR	Common Stock	Sale	$259,780	-480	-70%	$541.21	210	13 Mar 2026	Direct	F1, F8
transaction	UTHR	Common Stock	Sale	$43,363	-80	-38%	$542.04	130	13 Mar 2026	Direct	F1, F9
holding	UTHR	Common Stock						166	13 Mar 2026	by Spouse
holding	UTHR	Common Stock						324,518	13 Mar 2026	by Trust	F10
holding	UTHR	Common Stock						258,117	13 Mar 2026	by Trust	F11
holding	UTHR	Common Stock						45,596	13 Mar 2026	by Trust	F12
holding	UTHR	Common Stock						10,962	13 Mar 2026	by Trust	F13

Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Underlying Class	Amount	Exercise Price	Ownership	Footnotes
transaction	UTHR	Stock Option	Options Exercise		-9,500	-6.1%	$0.000000^*	145,000	13 Mar 2026	Common Stock	9,500	$146.03	Direct	F1

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Buy Plan / Sale Plan: These are also open market purchases/sales of shares, but in this case the transaction is part of a trading plan. Rule 10b5-1 allows insiders to setup a trading plan to buy/sell stocks over a certain period of time. Since the purchases/sales are predetermined, this protects the insiders from violating insider trading law.

Transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c).

Explanation of Responses:

Id	Content
F1	This exercise of stock options and sale of the resulting shares of common stock was pursuant to a pre-arranged 10b5-1 trading plan adopted by the reporting person on November 7, 2025. This plan will continue until the earlier of: (a) the exercise of 1,734,410 stock options, all of which expire on March 17, 2027; or (b) December 31, 2026.
F10	Shares held in family trusts as to which the Reporting Person shares investment power and the Reporting Person and/or immediate family members are beneficiaries.
F11	Shares held in family trusts as to which the Reporting Person's spouse is sole trustee and sole beneficiary or co-trustee and settlor with power to revoke.
F12	Shares held in family trusts as to which the Reporting Person's spouse shares investment power and the Reporting Person and/or immediate family members are beneficiaries.
F13	Shares held in family trusts as to which the Reporting Person is sole trustee and sole beneficiary or co-trustee and settlor with power to revoke.
F2	This transaction was executed in multiple trades at prices ranging from $534.80 to $535.79. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.
F3	This transaction was executed in multiple trades at prices ranging from $535.80 to $536.78. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.
F4	This transaction was executed in multiple trades at prices ranging from $536.82 to $537.81. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.
F5	This transaction was executed in multiple trades at prices ranging from $537.82 to $538.80. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.
F6	This transaction was executed in multiple trades at prices ranging from $538.82 to $539.78. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.
F7	This transaction was executed in multiple trades at prices ranging from $539.84 to $540.79. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.
F8	This transaction was executed in multiple trades at prices ranging from $540.93 to $541.73. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.
F9	This transaction was executed in multiple trades at prices ranging from $542.03 to $542.04. The price reported above reflects the weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.