| Name | Relationship | Address | Signature | Signature date | CIK |
|---|---|---|---|---|---|
| Meeker David P | President and CEO, Director | C/O RHYTHM PHARMACEUTICALS, INC., 222 BERKELEY STREET, 12TH FLOOR, BOSTON | /s/ Stephen Vander Stoep, Attorney-in-Fact for David Meeker | 13 Feb 2026 | 0001385155 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Underlying Class | Amount | Exercise Price | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | RYTM | Restricted Stock Units | Award | $0 | +71,900 | $0.000000 | 71,900 | 11 Feb 2026 | Common Stock | 71,900 | Direct | F1, F2 | ||
| transaction | RYTM | Stock Options (Right to Buy) | Award | $0 | +107,850 | $0.000000 | 107,850 | 11 Feb 2026 | Common Stock | 107,850 | $98.47 | Direct | F3 |
| Id | Content |
|---|---|
| F1 | Each restricted stock unit represents a contingent right to receive one share of Issuer common stock. |
| F2 | The restricted stock units vest as to 25% of the total shares on each of February 1, 2027, February 1, 2028, February 1, 2029 and February 1, 2030. The restricted stock units have no expiration date. |
| F3 | The stock options were granted on February 11, 2026. The options vest and become exercisable in 16 substantially equal installments upon the Reporting Person's completion of each three full months of successive service to the Issuer following the grant date. |