| Name | Relationship | Address | Signature | Signature date | CIK |
|---|---|---|---|---|---|
| Kaplan Johanne | Chief Development Officer | C/O PROMIS NEUROSCIENCES INC., 1920 YONGE STREET, SUITE 200, TORONTO, ONTARIO, CANADA | /s/ Max A. Milbury, Attorney in Fact for Johanne Kaplan | 05 Feb 2026 | 0001967717 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | PMN | Common Shares | Award | $24,988 | +2,060 | +817% | $12.13 | 2,312 | 03 Feb 2026 | Direct | F1, F2 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Underlying Class | Amount | Exercise Price | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | PMN | Warrants to purchase Common Shares | Award | +2,060 | 2,060 | 03 Feb 2026 | Common Shares | 2,060 | $14.40 | Direct | F1, F3 |
| Id | Content |
|---|---|
| F1 | On February 3, 2026, pursuant to a Securities Purchase Agreement entered into by the Company with selected investors, the Reporting Person acquired 2,060 of the Company's common shares, no par value (the "Common Shares") and Common Share purchase warrants (the "Common Share Warrants") to purchase 2,060 Common Shares. The purchase price was $12.13 per Common Share and Common Share Warrant. |
| F2 | Reflects a one-for-twenty-five reverse split of the Company's Common Shares effected on November 28, 2025. |
| F3 | The Common Share Warrants will expire upon the earlier of (i) February 3, 2031 or (ii) within 60 days of the public announcement via press release or the filing of a Current Report on Form 8-K of topline data from the cohorts treated with single ascending doses of PMN310. |