Darren Sherman - 02 Jan 2026 Form 4 Insider Report for Orchestra BioMed Holdings, Inc. (OBIO)

Role: President and Chief Operating Officer, Director
Signature: /s/ Andrew Taylor, Attorney-in-Fact
Issuer symbol: OBIO
Transactions as of: 02 Jan 2026
Net transactions value: -$24,084
Form type: 4
Filing time: 02 Jan 2026, 18:53:59 UTC
Previous filing: 26 Nov 2025
Next filing: 06 Feb 2026
SEC: View on sec.gov

Reporting Owners (1)

Name	Relationship	Address	Signature	Signature date	CIK
Sherman Darren	President and Chief Operating Officer, Director	C/O ORCHESTRA BIOMED HOLDINGS, INC., 150 UNION SQUARE DRIVE, NEW HOPE	/s/ Andrew Taylor, Attorney-in-Fact	02 Jan 2026	0001723524

Transactions Table

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Ownership	Footnotes
transaction	OBIO	Common Stock, par value $0.0001 per share	Tax liability	$24,084	-5,588	-0.66%	$4.31	840,569	02 Jan 2026	Direct	F1

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id	Content
F1	Represents the withholding of shares by the Issuer to satisfy tax withholding obligations in connection with vesting of restricted stock units. No shares were sold in the market as a result of the vesting of these restricted stock units and the satisfaction of tax withholding obligations.

Remarks:

President and Chief Operating Officer