| Name | Relationship | Address | Signature | Signature date | CIK |
|---|---|---|---|---|---|
| Fairmount Funds Management LLC | Director, 10%+ Owner | 200 BARR HARBOR DRIVE, SUITE 400, WEST CONSHOHOCKEN | /s/ Tomas Kiselak, Managing Member of Fairmount Funds Management LLC | 08 Dec 2025 | 0001802528 |
| Fairmount Healthcare Fund II L.P. | Director, 10%+ Owner | 200 BARR HARBOR DRIVE, SUITE 400, WEST CONSHOHOCKEN | /s/ Tomas Kiselak, Managing Member of Fairmount Healthcare Fund II, L.P. | 08 Dec 2025 | 0001769651 |
| Kiselak Tomas | Director, 10%+ Owner | 200 BARR HARBOR DRIVE, SUITE 400, WEST CONSHOHOCKEN | /s/ Tomas Kiselak | 08 Dec 2025 | 0001830177 |
| Harwin Peter Evan | Director, 10%+ Owner | 200 BARR HARBOR DRIVE, SUITE 400, WEST CONSHOHOCKEN | /s/ Peter Harwin | 08 Dec 2025 | 0001663607 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | CBIO | Ordinary Shares | Purchase | $18,237,600 | +1,360,000 | +98% | $13.41 | 2,747,866 | 04 Dec 2025 | By Fairmount Healthcare Fund II L.P. | F1 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Underlying Class | Amount | Exercise Price | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | CBIO | Pre-Funded Warrant (Right to Buy) | Purchase | $1,762,399 | +131,434 | +8% | $13.41 | 1,768,140 | 04 Dec 2025 | Ordinary Shares | 131,434 | $0.001000 | By Fairmount Healthcare Fund II L.P. | F1, F2 |
| Id | Content |
|---|---|
| F1 | Fairmount Funds Management LLC ("Fairmount") is the investment manager for Fairmount Healthcare Fund II L.P. The managers of Fairmount are Peter Harwin and Tomas Kiselak. Fairmount, Mr. Harwin, and Mr. Kiselak disclaim beneficial ownership of any of the reported securities, except to the extent of their pecuniary interest therein. |
| F2 | The Pre-Funded Warrants have no expiration date and are exercisable at any time after the date of issuance. A holder of Pre-Funded Warrants may not exercise the Pre-Funded Warrant if the holder, together with its affiliates, would beneficially own more than 9.99% of the number of outstanding shares of common stock of the Issuer immediately after giving effect to such exercise. |
Fairmount may be deemed a director by deputization of Issuer by virtue of the fact that Peter Harwin serves on the board of directors of the Issuer and is a manager of Fairmount.