Andrew Lawrence Taylor - 25 Nov 2025 Form 4 Insider Report for Orchestra BioMed Holdings, Inc. (OBIO)

Role: Chief Financial Officer
Signature: /s/ Andrew Taylor
Issuer symbol: OBIO
Transactions as of: 25 Nov 2025
Net transactions value: -$16,430
Form type: 4
Filing time: 26 Nov 2025, 16:05:48 UTC
Previous filing: 19 Sep 2025
Next filing: 12 Dec 2025
SEC: View on sec.gov

Reporting Owners (1)

Name	Relationship	Address	Signature	Signature date	CIK
Taylor Andrew Lawrence	Chief Financial Officer	C/O ORCHESTRA BIOMED HOLDINGS, INC., 150 UNION SQUARE DRIVE, NEW HOPE	/s/ Andrew Taylor	26 Nov 2025	0001723889

Transactions Table

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Ownership	Footnotes
transaction	OBIO	Common Stock, par value $0.0001 per share	Tax liability	$16,430	-3,071	-0.66%	$5.35	463,615	25 Nov 2025	Direct	F1

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id	Content
F1	Represents the withholding of shares by the Issuer to satisfy tax withholding obligations in connection with vesting of restricted stock units. No shares were sold in the market as a result of the vesting of these restricted stock units and the satisfaction of tax withholding obligations.