-
Signature
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/s/ Stephen Vander Stoep, attorney-in-fact for Pamela J. Cramer
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Issuer symbol
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RYTM
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Transactions as of
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07 Nov 2025
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Transactions value $
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-$2,000,740
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Form type
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4
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Filing time
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12 Nov 2025, 16:30:12 UTC
Reporting Owners (1)
| Name |
Relationship |
Address |
Signature |
Signature date |
CIK |
| Cramer Pamela J. |
Chief Human Resources Officer |
C/O RHYTHM PHARMACEUTICALS, INC., 222 BERKELEY STREET, 12TH FLOOR, BOSTON |
/s/ Stephen Vander Stoep, attorney-in-fact for Pamela J. Cramer |
12 Nov 2025 |
0001873517 |
Transactions Table
| Type |
Sym |
Class |
Transaction |
Value $ |
Shares |
Change % |
* Price $ |
Shares After |
Date |
Ownership |
Footnotes |
| transaction |
RYTM |
Common Stock |
Options Exercise |
$167K |
+8.81K |
+42.3% |
$19.02 |
29.6K |
07 Nov 2025 |
Direct |
|
| transaction |
RYTM |
Common Stock |
Options Exercise |
$71.7K |
+10.5K |
+35.61% |
$6.80 |
40.2K |
07 Nov 2025 |
Direct |
|
| transaction |
RYTM |
Common Stock |
Sale |
-$1.91M |
-19.4K |
-48.18% |
$98.82 |
20.8K |
07 Nov 2025 |
Direct |
F1 |
| transaction |
RYTM |
Common Stock |
Options Exercise |
$23.9K |
+3.52K |
+16.89% |
$6.80 |
24.3K |
10 Nov 2025 |
Direct |
|
| transaction |
RYTM |
Common Stock |
Sale |
-$352K |
-3.52K |
-14.45% |
$100.00 |
20.8K |
10 Nov 2025 |
Direct |
F1 |
Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)
| Type |
Sym |
Class |
Transaction |
Value $ |
Shares |
Change % |
* Price $ |
Shares After |
Date |
Underlying Class |
Amount |
Exercise Price |
Ownership |
Footnotes |
| transaction |
RYTM |
Stock Options (Right to Buy) |
Options Exercise |
$0 |
-8.81K |
-62.62% |
$0.00 |
5.26K |
07 Nov 2025 |
Common Stock |
8.81K |
$19.02 |
Direct |
F2 |
| transaction |
RYTM |
Stock Options (Right to Buy) |
Options Exercise |
$0 |
-10.5K |
-59.99% |
$0.00 |
7.04K |
07 Nov 2025 |
Common Stock |
10.5K |
$6.80 |
Direct |
F3 |
| transaction |
RYTM |
Stock Options (Right to Buy) |
Options Exercise |
$0 |
-3.52K |
-49.96% |
$0.00 |
3.52K |
10 Nov 2025 |
Common Stock |
3.52K |
$6.80 |
Direct |
F3 |
* An asterisk sign (*) next to the price indicates that the price is likely invalid.
Buy Plan / Sale Plan: These are also open market purchases/sales of shares, but in this case the transaction is part of a trading plan. Rule 10b5-1 allows insiders to setup a trading plan to buy/sell stocks over a certain period of time. Since the purchases/sales are predetermined, this protects the insiders from violating insider trading law.
Transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c).
Explanation of Responses: