| Name | Relationship | Address | Signature | Signature date | CIK |
|---|---|---|---|---|---|
| Aryeh Jason | Director | C/O ORCHESTRA BIOMED HOLDINGS, INC., 150 UNION SQUARE DRIVE, NEW HOPE | /s/ Andrew Taylor, Attorney-in-Fact | 19 Sep 2025 | 0001376960 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | OBIO | Common Stock, par value $0.0001 per share | Purchase | $2,450 | +1,000 | +0.93% | $2.45 | 108,482 | 19 Sep 2025 | Direct |