| Name | Relationship | Address | Signature | Signature date | CIK |
|---|---|---|---|---|---|
| Hochman David P | Chief Executive Officer and Chairperson, Director | C/O ORCHESTRA BIOMED HOLDINGS, INC., 150 UNION SQUARE DRIVE, NEW HOPE | /s/ Andrew Taylor, Attorney-in-Fact | 19 Sep 2025 | 0001292834 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | OBIO | Common Stock, par value $0.0001 per share ("Common Stock") | Tax liability | $99,273 | -40,355 | -6.2% | $2.46 | 611,105 | 17 Sep 2025 | Direct | F1 |
| transaction | OBIO | Common Stock | Tax liability | $8,076 | -3,283 | -0.73% | $2.46 | 446,048 | 17 Sep 2025 | By the DPH 2008 Trust | F1 |
| Id | Content |
|---|---|
| F1 | Represents the withholding of shares by the Issuer to satisfy tax withholding obligations in connection with vesting of restricted stock units. No shares were sold in the market as a result of the vesting of these restricted stock units and the satisfaction of tax withholding obligations. |
Chief Executive Officer and Chairperson