| Name | Relationship | Address | Signature | Signature date | CIK |
|---|---|---|---|---|---|
| Taylor Andrew Lawrence | Chief Financial Officer | C/O ORCHESTRA BIOMED HOLDINGS, INC., 150 UNION SQUARE DRIVE, NEW HOPE | /s/ Andrew Taylor | 25 Aug 2025 | 0001723889 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | OBIO | Common Stock, par value $0.0001 per share | Purchase | $5,100 | +2,000 | +0.42% | $2.55 | 482,788 | 25 Aug 2025 | Direct |