| Name | Relationship | Address | Signature | Signature date | CIK |
|---|---|---|---|---|---|
| Fairmount Funds Management LLC | Director, 10%+ Owner | 200 BARR HARBOR DRIVE, SUITE 400, WEST CONSHOHOCKEN | /s/ Tomas Kiselak, Managing Member of Fairmount Funds Management LLC | 23 Jun 2025 | 0001802528 |
| Fairmount Healthcare Fund II L.P. | Director, 10%+ Owner | 200 BARR HARBOR DRIVE, SUITE 400, WEST CONSHOHOCKEN | /s/ Tomas Kiselak, Managing Member of Fairmount Healthcare Fund II L.P. | 23 Jun 2025 | 0001769651 |
| Kiselak Tomas | Director, 10%+ Owner | 200 BARR HARBOR DRIVE, SUITE 400, WEST CONSHOHOCKEN | /s/ Tomas Kiselak | 23 Jun 2025 | 0001830177 |
| Harwin Peter Evan | Director, 10%+ Owner | 200 BARR HARBOR DRIVE, SUITE 400, WEST CONSHOHOCKEN | /s/ Peter Harwin | 23 Jun 2025 | 0001663607 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Underlying Class | Amount | Exercise Price | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | CBIO | Stock Option (Right to Buy) | Award | $0 | +9,023 | $0.000000 | 9,023 | 23 Jun 2025 | Ordinary Shares | 9,023 | $15.30 | By: Peter Harwin | F1, F2 |
| Id | Content |
|---|---|
| F1 | This option represents a right to purchase 9,023 of the Issuer's ordinary shares, which vest in full on the earlier of (i) June 23, 2026 or (ii) the date of the Issuer's next annual meeting of shareholders, in each case, subject to the Reporting Person's continued service to the Issuer. |
| F2 | Under Mr. Harwin's arrangement with Fairmount Funds Management LLC ("Fairmount"), Mr. Harwin holds the option for one or more investment vehicles managed by Fairmount (each, a "Fairmount Fund"). Mr. Harwin is obligated to turn over to Fairmount any net cash or shares received from the option for the benefit of such Fairmount Fund. Mr. Harwin therefore disclaims beneficial ownership of the option and underlying ordinary shares. Fairmount disclaims beneficial ownership of any of the reported securities, except to the extent of its pecuniary interest therein. |
Fairmount and Fairmount Healthcare Fund II LP may each be deemed a director by deputization of the Issuer by virtue of the fact that Peter Harwin serves on the board of directors of the Issuer and is a manager of Fairmount.