| Name | Relationship | Address | Signature | Signature date | CIK |
|---|---|---|---|---|---|
| Fletcher Aaron G.L. | 10%+ Owner | C/O BIOS PARTNERS, 1751 RIVER RUN SUITE 400, FORT WORTH | Aaron G.L. Fletcher By: /s/ John Fucci, as attorney-in-fact | 29 May 2025 | 0001789490 |
| BIOS Fund I, LP | 10%+ Owner | C/O BIOS PARTNERS, 1751 RIVER RUN SUITE 400, FORT WORTH | Bios Fund I, LP By: Bios Equity Partners, LP, its general partner By: Bios Capital Management, LP, its general partner By: Bios Advisors GP, LLC, its general partner By: /s/ John Fucci, as attorney-in-fact | 29 May 2025 | 0001697316 |
| BIOS Fund I QP, LP | 10%+ Owner | C/O BIOS PARTNERS, 1751 RIVER RUN SUITE 400, FORT WORTH | Bios Fund I QP, LP By: Bios Equity Partners, LP, its general partner By: Bios Capital Management, LP, its general partner By: Bios Advisors GP, LLC, its general partner By: /s/ John Fucci, as attorney-in-fact | 29 May 2025 | 0001700297 |
| BIOS Fund II, LP | 10%+ Owner | C/O BIOS PARTNERS, 1751 RIVER RUN SUITE 400, FORT WORTH | Bios Fund II, LP By: Bios Equity Partners II, LP, its general partner By: Bios Capital Management, LP, its general partner By: Bios Advisors GP, LLC, its general partner By: /s/ John Fucci, as attorney-in-fact | 29 May 2025 | 0001714576 |
| BIOS Fund II QP, LP | 10%+ Owner | C/O BIOS PARTNERS, 1751 RIVER RUN SUITE 400, FORT WORTH | Bios Fund II QP, LP By: Bios Equity Partners II, LP, its general partner By: Bios Capital Management, LP, its general partner By: Bios Advisors GP, LLC, its general partner By: /s/ John Fucci, as attorney-in-fact | 29 May 2025 | 0001716869 |
| BIOS Fund II NT, LP | 10%+ Owner | C/O BIOS PARTNERS, 1751 RIVER RUN SUITE 400, FORT WORTH | Bios Fund II NT, LP By: Bios Equity Partners II, LP, its general partner By: Bios Capital Management, LP, its general partner By: Bios Advisors GP, LLC, its general partner By: /s/ John Fucci, as attorney-in-fact | 29 May 2025 | 0001728851 |
| Bios Equity Partners, LP | 10%+ Owner | C/O BIOS PARTNERS, 1751 RIVER RUN SUITE 400, FORT WORTH | Bios Equity Partners, LP By: Bios Capital Management, LP, its general partner By: Bios Advisors GP, LLC, its general partner By: /s/ John Fucci, as attorney-in-fact | 29 May 2025 | 0001813314 |
| Bios Equity Partners II, LP | 10%+ Owner | C/O BIOS PARTNERS, 1751 RIVER RUN SUITE 400, FORT WORTH | Bios Equity Partners II, LP By: Bios Capital Management, LP, its general partner By: Bios Advisors GP, LLC, its general partner By: /s/ John Fucci, as attorney-in-fact | 29 May 2025 | 0001813313 |
| BIOS Capital Management, LP | 10%+ Owner | C/O BIOS PARTNERS, 1751 RIVER RUN SUITE 400, FORT WORTH | Bios Capital Management, LP By: Bios Advisors GP, LLC, its general partner By: /s/ John Fucci, as attorney-in-fact | 29 May 2025 | 0001813845 |
| BIOS Advisors GP, LLC | 10%+ Owner | C/O BIOS PARTNERS, 1751 RIVER RUN SUITE 400, FORT WORTH | Bios Advisors GP, LLC By: /s/ John Fucci, as attorney-in-fact | 29 May 2025 | 0001813844 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | LTRN | Common Stock | Sale | $11,560 | -3,790 | -1.7% | $3.05 | 213,763 | 27 May 2025 | By Bios Fund I QP, LP | F1, F4, F5, F6 |
| transaction | LTRN | Common Stock | Sale | $7,755 | -2,702 | -1.3% | $2.87 | 211,061 | 28 May 2025 | By Bios Fund I QP, LP | F2, F4, F5, F6 |
| transaction | LTRN | Common Stock | Sale | $11,026 | -3,639 | -1.7% | $3.03 | 207,422 | 29 May 2025 | By Bios Fund I QP, LP | F3, F4, F5, F6 |
| transaction | LTRN | Common Stock | Sale | $19,761 | -6,479 | -1.7% | $3.05 | 365,471 | 27 May 2025 | By Bios Fund I, LP | F1, F4, F5, F6 |
| transaction | LTRN | Common Stock | Sale | $13,259 | -4,620 | -1.3% | $2.87 | 360,851 | 28 May 2025 | By Bios Fund I, LP | F2, F4, F5, F6 |
| transaction | LTRN | Common Stock | Sale | $18,850 | -6,221 | -1.7% | $3.03 | 354,630 | 29 May 2025 | By Bios Fund I, LP | F3, F4, F5, F6 |
| transaction | LTRN | Common Stock | Sale | $3,050 | -1,000 | -1.7% | $3.05 | 56,467 | 27 May 2025 | By Bios Fund II NT, LP | F1, F4, F5, F6 |
| transaction | LTRN | Common Stock | Sale | $2,049 | -714 | -1.3% | $2.87 | 55,753 | 28 May 2025 | By Bios Fund II NT, LP | F2, F4, F5, F6 |
| transaction | LTRN | Common Stock | Sale | $2,912 | -961 | -1.7% | $3.03 | 54,792 | 29 May 2025 | By Bios Fund II NT, LP | F3, F4, F5, F6 |
| transaction | LTRN | Common Stock | Sale | $22,808 | -7,478 | -1.7% | $3.05 | 421,808 | 27 May 2025 | By Bios Fund II QP, LP | F1, F4, F5, F6 |
| transaction | LTRN | Common Stock | Sale | $15,303 | -5,332 | -1.3% | $2.87 | 416,476 | 28 May 2025 | By Bios Fund II QP, LP | F2, F4, F5, F6 |
| transaction | LTRN | Common Stock | Sale | $21,755 | -7,180 | -1.7% | $3.03 | 409,296 | 29 May 2025 | By Bios Fund II QP, LP | F3, F4, F5, F6 |
| transaction | LTRN | Common Stock | Sale | $6,984 | -2,290 | -1.7% | $3.05 | 129,163 | 27 May 2025 | By Bios Fund II, LP | F1, F4, F5, F6 |
| transaction | LTRN | Common Stock | Sale | $4,684 | -1,632 | -1.3% | $2.87 | 127,531 | 28 May 2025 | By Bios Fund II, LP | F2, F4, F5, F6 |
| transaction | LTRN | Common Stock | Sale | $6,663 | -2,199 | -1.7% | $3.03 | 125,332 | 29 May 2025 | By Bios Fund II, LP | F3, F4, F5, F6 |
| holding | LTRN | Common Stock | 26,093 | 27 May 2025 | By BP Directors, LP | F4, F5, F6 |
| Id | Content |
|---|---|
| F1 | The price reported in Column 4 is a weighted average price. On May 27, 2025 each of Bios Fund I QP, LP ("Bios Fund I QP"), Bios Fund I, LP ("Bios Fund I"), Bios Fund II NT, LP ("Bios Fund II NT"), Bios Fund II QP, LP ("Bios Fund II QP") and Bios Fund II, LP ("Bios Fund II") sold shares in multiple transactions at prices ranging from $2.87 to $3.21, inclusive. The reporting persons undertake to provide to the Issuer, any security holder of the Isser, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnotes (1) and (2) to this Form 4. |
| F2 | The price reported in Column 4 is a weighted average price. On May 28, 2025, each of Bios Fund I QP, Bios Fund I, Bios Fund II NT, Bios Fund II QP and Bios Fund II sold shares in multiple transactions at prices ranging from $2.85 to $2.94 inclusive. |
| F3 | The price reported in Column 4 is a weighted average price. On May 29, 2025, each of Bios Fund I QP, Bios Fund I, Bios Fund II NT, Bios Fund II QP and Bios Fund II sold shares in multiple transactions at prices ranging from $3.00 to $3.13 inclusive. |
| F4 | Bios Equity Partners, LP ("Bios Equity I") is the general partner of the following entities: Bios Fund I, Bios Fund I QP and BP Directors, LP ("Bios Directors"). Bios Equity Partners II, LP ("Bios Equity II") is the general partner of the following entities: Bios Fund II, Bios Fund II QP and Bios Fund II NT. Cavu Management, LP ("Cavu Management"), an entity managed and controlled by Leslie W. Kreis, Jr and Bios Capital Management, LP ("Bios Management"), an entity managed and controlled by Aaron Glenn Louis Fletcher, are each a general partner of Bios Equity I and Bios Equity II. Cavu Advisors LLC ("Cavu Advisors"), an entity that is managed and controlled by Mr. Kreis, is the general partner of Cavu Management. Bios Advisors GP, LLC ("Bios Advisors"), an entity that is managed and controlled by Mr. Fletcher, is the general partner of Bios Management. |
| F5 | Mr. Kreis, Cavu Management, Cavu Advisors, Mr. Fletcher, Bios Management and Bios Advisors each share voting and investment control with respect to the shares held by Bios Fund I, Bios Fund I QP, Bios Directors, Bios Fund II, Bios Fund II QP and Bios Fund II NT (collectively, the "Bios Equity Entities"). Because of the relationship between Mr. Kreis, Mr. Fletcher, Cavu Management, Bios Management, Cavu Advisors, Bios Advisors and the Bios Equity Entities, Mr. Kreis, Mr. Fletcher, Cavu Management, Bios Management, Cavu Advisors and Bios Advisors each may be deemed to beneficially own the shares held directly by the Bios Equity Entities. |
| F6 | For purposes of Section 16 of the Securities Exchange Act of 1934, as amended, each Reporting Person disclaims beneficial ownership of any such securities, except to the extent of his/its pecuniary interest therein, if any, and this report shall not be deemed an admission that such Reporting Person is the beneficial owner of such securities for purposes of Section 16 or otherwise. |
Exhibit 24 - Power of Attorney. This Form 4 is the first of two Forms 4 filed relating to the same event. The Form 4 has been split into two filings because there are more than 10 reporting persons in total, and the SEC's EDGAR filing system limits a single Form 4 to a maximum of 10 reporting person. The second Form 4 will be filed by Leslie W. Kreis as the designated filer.