Maria-Luisa Maccecchini - 06 Feb 2023 Form 4 Insider Report for Annovis Bio, Inc. (ANVS)

Role: President and CEO, Director, 10%+ Owner
Signature: /s/ Henry Hagopian, III, Attorney-in-Fact for Maria L. Maccecchini
Issuer symbol: ANVS
Transactions as of: 06 Feb 2023
Net transactions value: +$7,386
Form type: 4
Filing time: 08 Feb 2023, 16:11:34 UTC
Previous filing: 20 Jan 2023
Next filing: 11 Apr 2023
SEC: View on sec.gov

Transactions Table

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Ownership	Footnotes
transaction	ANVS	Common Stock	Options Exercise	$7,386	+52,755	+5.3%	$0.1400^*	1,040,489	06 Feb 2023	Direct

Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Underlying Class	Amount	Exercise Price	Ownership	Footnotes
transaction	ANVS	Stock Option (right to buy)	Options Exercise	$0	-52,755	-100%	$0.000000^*	0	06 Feb 2023	Common Stock	52,755	$0.1400	Direct	F1

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id	Content
F1	All of the shares underlying the option are fully vested and exercisable.