Pamela J. Cramer - 26 Jul 2022 Form 4 Insider Report for RHYTHM PHARMACEUTICALS, INC. (RYTM)

Role: Chief Human Resources Officer
Signature: /s/ Hunter Smith, attorney-in-fact for Pamela J. Cramer
Issuer symbol: RYTM
Transactions as of: 26 Jul 2022
Net transactions value: -$10,524
Form type: 4
Filing time: 28 Jul 2022, 16:31:53 UTC
Previous filing: 11 Feb 2022
Next filing: 23 Aug 2022
SEC: View on sec.gov

Transactions Table

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Ownership	Footnotes
transaction	RYTM	Common Stock	Options Exercise		+3,125			3,125	26 Jul 2022	Direct	F1
transaction	RYTM	Common Stock	Sale	$10,524	-901	-29%	$11.68	2,224	27 Jul 2022	Direct	F2

Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Underlying Class	Amount	Exercise Price	Ownership	Footnotes
transaction	RYTM	Restricted Stock Units	Options Exercise	$0	+3,125	+50%	$0.000000	9,375	26 Jul 2022	Common Stock	3,125		Direct	F1, F3

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id	Content
F1	Each restricted stock unit represents a contingent right to receive one share of Issuer common stock.
F2	The sale reported in the Form 4 was effected pursuant to a Rule 10b5-1 instruction solely with the intent to cover withholding taxes in connection with the vesting of certain previously reported Restricted Share Units.
F3	The restricted stock units vest or have vested as to 25% of the total shares on each of July 26, 2022, July 26, 2023, July 26, 2024 and July 26, 2025. The restricted stock units have no expiration date.