Christine A. Pellizzari - Oct 6, 2021 Form 4 Insider Report for Science 37 Holdings, Inc. (SNCE)

Role: Chief Legal Officer
Signature: /s/ Christine Pellizzari
Stock symbol: SNCE
Transactions as of: Oct 6, 2021
Transactions value $: $0
Form type: 4
Date filed: 10/8/2021, 09:58 PM
Previous filing: Jul 6, 2021
Next filing: Jan 11, 2022

Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Underlying Class	Amount	Exercise Price	Ownership	Footnotes
transaction	SNCE	Stock Option	Award		+1.27M			1.27M	Oct 6, 2021	Common Stock	1.27M	$9.49	Direct	F1, F2

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id	Content
F1	Pursuant to the business combination of LifeSci Acquisition II Corp and Science 37, Inc. ("Old Science 37"), as contemplated by that certain agreement and plan of merger, dated May 6, 2021 (the "Merger Agreement"), (a) each share of common stock of Old Science 37 outstanding immediately prior to the effective time of the business combination was converted into approximately 1.8153 shares of the Issuer's Common Stock, (b) (the "Conversion Ratio"); and (b) each outstanding stock option of Old Science 37 was converted into a corresponding option to purchase shares of the Issuer's Common Stock as adjusted for the Conversion Ratio
F2	Represents an option vesting with respect to 25% of the shares subject to the option on the first anniversary of the vesting start date, July 8, 2021, and with respect to 1/48th of the shares subject to the option on each monthly anniversary of the applicable vesting start date thereafter, subject to the executive's continued service through the applicable vesting date.

Content

Pursuant to the business combination of LifeSci Acquisition II Corp and Science 37, Inc. ("Old Science 37"), as contemplated by that certain agreement and plan of merger, dated May 6, 2021 (the "Merger Agreement"), (a) each share of common stock of Old Science 37 outstanding immediately prior to the effective time of the business combination was converted into approximately 1.8153 shares of the Issuer's Common Stock, (b) (the "Conversion Ratio"); and (b) each outstanding stock option of Old Science 37 was converted into a corresponding option to purchase shares of the Issuer's Common Stock as adjusted for the Conversion Ratio

Represents an option vesting with respect to 25% of the shares subject to the option on the first anniversary of the vesting start date, July 8, 2021, and with respect to 1/48th of the shares subject to the option on each monthly anniversary of the applicable vesting start date thereafter, subject to the executive's continued service through the applicable vesting date.