No securities are beneficially owned.
Amrit Nagpal is a managing director of Redmile Group, LLC ("Redmile"), and was elected to the Issuer's board of directors as a representative of Redmile. As a result, each of Redmile, Jeremy Green, as principal of Redmile, and Redmile Biopharma Investments II, L.P., which directly owned the Issuer's convertible preferred stock which entitled the holder to appoint one director, are a director by deputization for purposes of Section 16 of the Securities Exchange Act of 1934, as amended.