Rtw Investments, Lp - Jan 26, 2023 Form 4 Insider Report for Orchestra BioMed Holdings, Inc. (OBIO)

Role: 10%+ Owner
Signature: /s/ Roderick Wong, for RTW Investments, LP, By: Roderick Wong, M.D., its Managing Partner
Stock symbol: OBIO
Transactions as of: Jan 26, 2023
Transactions value $: $0
Form type: 4
Date filed: 1/30/2023, 04:11 PM
Previous filing: Jan 26, 2023
Next filing: Mar 24, 2023

Transactions Table

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Ownership	Footnotes
transaction	OBIO	Common Stock	Award		+2.31M	+82.25%		5.12M	Jan 26, 2023	See footnote	F1, F2

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id	Content
F1	Received in exchange for 4,967,741 shares of Orchestra BioMed, Inc. ("Orchestra") common stock in connection with the merger of Orchestra into Health Sciences Acquisitions Corporation 2 ("HSAC 2"), renamed upon closing "Orchestra BioMed Holdings, Inc." ("OBIO") at an exchange ratio of 0.465 shares of ordinary shares of HSAC2/OBIO for each whole share of Orchestra common stock. On the effective date of the merger, the closing price of OBIO's common stock was $13.31 per share.
F2	Held by certain affiliated funds managed by RTW Investments, LP ("RTW"), and Roderick Wong, M.D. serves as the Managing Partner and Chief Investment Officer of RTW. The reporting persons disclaim beneficial ownership of the reported securities for purposes of Section 16 under the Securities Exchange Act of 1934, as amended, except to the extent of their pecuniary interest therein.

Content

Received in exchange for 4,967,741 shares of Orchestra BioMed, Inc. ("Orchestra") common stock in connection with the merger of Orchestra into Health Sciences Acquisitions Corporation 2 ("HSAC 2"), renamed upon closing "Orchestra BioMed Holdings, Inc." ("OBIO") at an exchange ratio of 0.465 shares of ordinary shares of HSAC2/OBIO for each whole share of Orchestra common stock. On the effective date of the merger, the closing price of OBIO's common stock was $13.31 per share.

Held by certain affiliated funds managed by RTW Investments, LP ("RTW"), and Roderick Wong, M.D. serves as the Managing Partner and Chief Investment Officer of RTW. The reporting persons disclaim beneficial ownership of the reported securities for purposes of Section 16 under the Securities Exchange Act of 1934, as amended, except to the extent of their pecuniary interest therein.