Andrew Callos - 15 Mar 2026 Form 4 Insider Report for CYTOKINETICS INC (CYTK)

Role: EVP, Chief Commercial Officer
Signature: /s/ John O. Faurescu, attorney-in-fact for Mr. Callos
Issuer symbol: CYTK
Transactions as of: 15 Mar 2026
Net transactions value: $0
Form type: 4
Filing time: 17 Mar 2026, 16:08:05 UTC
Previous filing: 10 Mar 2026
Next filing: 16 Mar 2026
SEC: View on sec.gov

Reporting Owners (1)

Name	Relationship	Address	Signature	Signature date	CIK
Callos Andrew	EVP, Chief Commercial Officer	350 OYSTER POINT BLVD, SOUTH SAN FRANCISCO	/s/ John O. Faurescu, attorney-in-fact for Mr. Callos	17 Mar 2026	0001852129

Transactions Table

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Ownership	Footnotes
transaction	CYTK	Common Stock	Award		+20,646	+43%	$0.000000^*	68,504	15 Mar 2026	Direct	F1
transaction	CYTK	Common Stock	Award		+13,320	+19%	$0.000000^*	81,824	15 Mar 2026	Direct	F2

Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Underlying Class	Amount	Exercise Price	Ownership	Footnotes
transaction	CYTK	Incentive Stock Option (Right to Buy)	Award		+1,665		$0.000000^*	1,665	15 Mar 2026	Common Stock	1,665	$60.06	Direct	F3
transaction	CYTK	Non-Qualified Stock Option (Right to Buy)	Award		+29,480		$0.000000^*	29,480	15 Mar 2026	Common Stock	29,480	$60.06	Direct	F4

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id	Content
F1	Annual equity award comprised of restricted stock units ("RSUs") that convert on a 1:1 basis for shares of our common stock. RSUs vest, subject to the officer's continued employment with the company, as follows: 40% of the RSUs on the 1-year anniversary of the grant date, an additional 40% of the RSUs on the 2-year anniversary of the grant date, and the final 20% of the RSUs on the 3-year anniversary of the grant date. RSUs are subject to the company's Amended and Restated 2004 Equity Incentive Plan.
F2	Special supplemental equity award comprised of restricted stock units ("RSUs" that convert on a 1:1 basis for shares of our common stock. RSUs vest, subject to the officer's continued employment with the company, as follows: 50% of the RSUs on the 1-year anniversary of the grant date and 50% of the RSUs on the 2-year anniversary of the grant date. RSUs are subject to the company's Amended and Restated 2004 Equity Incentive Plan.
F3	Annual equity award comprised of stock options that vest in 48 equal monthly installments, subject to officer's continued employment with the company on each vesting date. Stock options are subject to the company's Amended and Restated 2004 Equity Incentive Plan.
F4	Annual equity award comprised of stock options that vest in 48 equal monthly installments, subject to officer's continued employment with the company on each vesting date. Stock options are subject to the company's Amended and Restated 2004 Equity Incentive Plan.