| Name | Relationship | Address | Signature | Signature date | CIK |
|---|---|---|---|---|---|
| Blum Robert I | President & CEO, Director | 350 OYSTER POINT BLVD, SOUTH SAN FRANCISCO | /s/ John O. Faurescu, attorney-in-fact for Mr. Blum | 23 Dec 2025 | 0001288859 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | CYTK | Common Stock | Options Exercise | $365,029 | +54,727 | +16% | $6.67 | 404,929 | 22 Dec 2025 | Direct | F1 |
| transaction | CYTK | Common Stock | Tax liability | $2,074,445 | -30,426 | -7.5% | $68.18 | 374,503 | 22 Dec 2025 | Direct | F2 |
| transaction | CYTK | Common Stock | Options Exercise | $110,095 | +16,506 | +4.4% | $6.67 | 391,009 | 22 Dec 2025 | Direct | F3 |
| holding | CYTK | Common Stock | 2,083 | 22 Dec 2025 | by Trust 1 | F4 | |||||
| holding | CYTK | Common Stock | 2,083 | 22 Dec 2025 | by Trust 2 | F5 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Underlying Class | Amount | Exercise Price | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | CYTK | Non-Qualified Stock Option (Right to Buy) | Options Exercise | $0 | -54,727 | -100% | $0.000000 | 0 | 22 Dec 2025 | Common Stock | 54,727 | $6.67 | Direct | |
| transaction | CYTK | Incentive Stock Option (Right to Buy) | Options Exercise | $0 | -16,506 | -100% | $0.000000 | 0 | 22 Dec 2025 | Common Stock | 16,506 | $6.67 | Direct |
| Id | Content |
|---|---|
| F1 | Net share settlement transaction. Not a market transaction. |
| F2 | Shares represent withholding of shares to cover exercise price and tax withholding obligations resulting from the net share settlement of 54,727 non-qualified stock options. |
| F3 | Cash exercise and hold transaction. |
| F4 | Shares held by The Bridget Blum 2003 Irrevocable Trust. |
| F5 | Shares held by The Brittany Blum 2003 Irrevocable Trust. |