PATRICK G. LEPORE - 12 Dec 2025 Form 4 Insider Report for VYNE Therapeutics Inc. (VYNE)

Role
Director
Signature
/s/ Mutya Harsch, Attorney-in-Fact
Issuer symbol
VYNE
Transactions as of
12 Dec 2025
Net transactions value
$0
Form type
4
Filing time
15 Dec 2025, 16:15:09 UTC
Previous filing
16 Jan 2025
SEC
View on sec.gov

Reporting Owners (1)

Name Relationship Address Signature Signature date CIK
LEPORE PATRICK G Director C/O VYNE THERAPEUTICS INC., P.O. BOX 125, STEWARTSVILLE /s/ Mutya Harsch, Attorney-in-Fact 15 Dec 2025 0001055404

Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)

Type Sym Class Transaction Value $ Shares Change % * Price $ Shares After Date Underlying Class Amount Exercise Price Ownership Footnotes
transaction VYNE Stock Option (right to buy) Award $0 +20,000 $0.000000 20,000 12 Dec 2025 Common Stock 20,000 $0.3756 Direct F1
* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id Content
F1 Represents the annual award to non-employee directors of the Issuer, awarded on the date of the Issuer's annual meeting of stockholders. The shares subject to the option vest on December 12, 2026, subject to the Reporting Person's continuous service through such date.