| Name | Relationship | Address | Signature | Signature date | CIK |
|---|---|---|---|---|---|
| Erdtmann Rainer M | President, Chief Operating Officer, Principal Financial Officer, and Principal Accounting Officer, Director | C/O BIOMEA FUSION, INC., 1599 INDUSTRIAL ROAD, SAN CARLOS | /s/ Rainer M. Erdtmann | 13 Aug 2025 | 0001455767 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | BMEA | Common Stock | Gift | $0 | -40K | -5.61% | $0.00 | 673K | 28 Jan 2025 | Direct | |
| transaction | BMEA | Common Stock | Gift | $0 | -10K | -1.49% | $0.00 | 663K | 31 Jan 2025 | Direct | |
| transaction | BMEA | Common Stock | Gift | $0 | +10K | +106.38% | $0.00 | 19.4K | 31 Jan 2025 | By daughter | |
| transaction | BMEA | Common Stock | Gift | $0 | -10K | -1.51% | $0.00 | 653K | 31 Jan 2025 | Direct | |
| transaction | BMEA | Common Stock | Gift | $0 | +10K | +100% | $0.00 | 20K | 31 Jan 2025 | By son | |
| transaction | BMEA | Common Stock | Gift | $0 | -10K | -1.53% | $0.00 | 643K | 31 Jan 2025 | Direct | |
| transaction | BMEA | Common Stock | Gift | $0 | +10K | +100% | $0.00 | 20K | 31 Jan 2025 | By daughter | |
| holding | BMEA | Common Stock | 175K | 28 Jan 2025 | See Footnote | F1 | |||||
| holding | BMEA | Common Stock | 1.13M | 28 Jan 2025 | See Footnote | F2 | |||||
| holding | BMEA | Common Stock | 228K | 28 Jan 2025 | See Footnote | F3 | |||||
| holding | BMEA | Common Stock | 252K | 28 Jan 2025 | See Footnote | F4 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Underlying Class | Amount | Exercise Price | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | BMEA | Stock Option (Right to Buy) | Award | $0 | +1.25M | $0.00 | 1.25M | 11 Aug 2025 | Common Stock | 1.25M | $1.53 | Direct | F5 |
| Id | Content |
|---|---|
| F1 | The shares are held by a trust having an independent trustee ("Trust 1"). The Reporting Person disclaims Section 16 beneficial ownership of the securities, except to the extent of his pecuniary interest therein, if any, and this report shall not be deemed to be an admission that he has beneficial ownership of such shares for Section 16 or any other purpose. |
| F2 | The shares are held by a trust having an independent trustee ("Trust 2"). The Reporting Person disclaims Section 16 beneficial ownership of the securities, except to the extent of his pecuniary interest therein, if any, and this report shall not be deemed to be an admission that he has beneficial ownership of such shares for Section 16 or any other purpose. |
| F3 | The shares are held directly by Point Sur Investors Fund I, LP ("Point Sur LP"). The General Partner of Point Sur LP is Point Sur Investors LLC. The Reporting Person is a managing member of Point Sur Investors, LLC and as such has voting and dispositive power over the securities held by Point Sur LP. The Reporting Person disclaims Section 16 beneficial ownership of the securities, except to the extent of his pecuniary interest therein, if any, and this report shall not be deemed to be an admission that he has beneficial ownership of such shares for Section 16 or any other purpose. |
| F4 | The shares are held directly by Point Sur Investors, LLC. The Reporting Person is a managing members of Point Sur Investors, LLC and as such has voting and dispositive power over the securities held by Point Sur Investors, LLC. The Reporting Person disclaims Section 16 beneficial ownership of the securities, except to the extent of his pecuniary interest therein, if any, and this report shall not be deemed to be an admission that he has beneficial ownership of such shares for Section 16 or any other purpose. |
| F5 | The option shall vest and become exercisable in 16 substantially equal quarterly installments after August 8, 2025, such that the award will be fully vested and exercisable on August 8, 2029, subject to the Reporting Person's continued service to the Issuer through each vesting date. |
President, Chief Operating Officer, Principal Financial Officer, and Principal Accounting Officer