| Name | Relationship | Address | Signature | Signature date | CIK |
|---|---|---|---|---|---|
| Ciongoli Gregory Austin | Director | C/O ZYMEWORKS INC., 108 PATRIOT DRIVE, SUITE A, MIDDLETOWN | /s/ Daniel Dex, Attorney-in-Fact | 12 Aug 2025 | 0002023732 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | ZYME | Common Stock | Award | $4,988,300 | +415,000 | +565% | $12.02 | 488,500 | 12 Aug 2025 | Direct | |
| holding | ZYME | Common Stock | 5,000 | 11 Aug 2025 | See footnote | F1 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Underlying Class | Amount | Exercise Price | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | ZYME | Stock Option (Right to Buy) | Award | $0 | +62,000 | $0.000000 | 62,000 | 11 Aug 2025 | Common Stock | 62,000 | $12.44 | Direct | F2 |
| Id | Content |
|---|---|
| F1 | Represents shares held by 4 Arrows Holdings, LLC, for which the reporting person is the manager. The reporting person exercises sole voting and dispositive power over these shares and disclaims beneficial ownership of these shares except to the extent of his pecuniary interest therein. |
| F2 | Stock options vest in 36 equal monthly installments starting one month after grant date of August 11, 2025. |