| Name | Relationship | Address | Signature | Signature date | CIK |
|---|---|---|---|---|---|
| Warner Douglas J | Chief Medical Officer | C/O TYRA BIOSCIENCES, INC., 2656 STATE STREET, CARLSBAD | /s/ Ali D. Fawaz, Attorney-in-Fact | 07 Aug 2025 | 0001941311 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Underlying Class | Amount | Exercise Price | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | TYRA | Stock Option (Right to Buy) | Award | $0 | +200,000 | $0.000000 | 200,000 | 07 Aug 2025 | Common Stock | 200,000 | $10.75 | Direct | F1 |
| Id | Content |
|---|---|
| F1 | 25% of the shares subject to the option shall vest on August 7, 2026, and 1/36th of the remaining number of shares subject to the option vest monthly thereafter, subject to the Reporting Person's continuous service to the Issuer through each vesting date. |