| Name | Relationship | Address | Signature | Signature date | CIK |
|---|---|---|---|---|---|
| Collier Kathryn J | Director | C/O REGULUS THERAPEUTICS, 4224 CAMPUS POINT COURT #210, SAN DIEGO | Christopher Aker, Attorney in Fact | 18 Jun 2025 | 0001737436 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | RGLS | Common Stock | Options Exercise | $13,820 | +1,396 | +2.1% | $9.90 | 67,844 | 16 Jun 2025 | Direct | |
| transaction | RGLS | Common Stock | Options Exercise | $25,780 | +2,604 | +4.2% | $9.90 | 65,240 | 17 Jun 2025 | Direct | |
| transaction | RGLS | Common Stock | Options Exercise | $20,460 | +2,325 | +3.8% | $8.80 | 62,915 | 17 Jun 2025 | Direct |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Underlying Class | Amount | Exercise Price | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | RGLS | Stock Option (Right to Buy) | Options Exercise | $0 | -1,396 | -35% | $0.000000 | 2,604 | 16 Jun 2025 | Common Stock | 1,396 | $9.90 | Direct | |
| transaction | RGLS | Stock Option (Right to Buy) | Options Exercise | $0 | -2,604 | -100% | $0.000000 | 0 | 17 Jun 2025 | Common Stock | 2,604 | $9.90 | Direct | |
| transaction | RGLS | Stock Option (Right to Buy) | Options Exercise | $0 | -2,325 | -100% | $0.000000 | 0 | 17 Jun 2025 | Common Stock | 2,325 | $8.80 | Direct |