| Name | Relationship | Address | Signature | Signature date | CIK |
|---|---|---|---|---|---|
| SKYLER JAY S | Director | C/O APPLIED THERAPEUTICS, INC., 545 FIFTH AVENUE, SUITE 1400, NEW YORK | /s/ Leslie D. Funtleyder, as attorney-in-fact | 11 Jun 2025 | 0001236386 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Underlying Class | Amount | Exercise Price | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | APLT | Stock Option (Right to Buy) | Award | $0 | +200,000 | $0.000000 | 200,000 | 09 Jun 2025 | Common Stock | 200,000 | $0.3950 | Direct | F1 |
| Id | Content |
|---|---|
| F1 | The shares subject to the option will vest in 36 equal monthly installments from the grant date, subject to the Reporting Person's continuous service through such vesting date. |
Exhibit 24 - Power of Attorney