William P. Forbes - 06 Jun 2025 Form 4 Insider Report for HERON THERAPEUTICS, INC. /DE/ (HRTX)

Role: EVP, Chief Development Officer
Signature: /s/ Kathryn Lester Attorney-in-Fact for William P. Forbes
Issuer symbol: HRTX
Transactions as of: 06 Jun 2025
Net transactions value: $0
Form type: 4
Filing time: 09 Jun 2025, 19:54:11 UTC
Previous filing: 02 May 2025
Next filing: 22 Jul 2025
SEC: View on sec.gov

Reporting Owners (1)

Name	Relationship	Address	Signature	Signature date	CIK
Forbes William P	EVP, Chief Development Officer	100 REGENCY FOREST DRIVE, SUITE 300, CARY	/s/ Kathryn Lester Attorney-in-Fact for William P. Forbes	09 Jun 2025	0001314760

Transactions Table

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Ownership	Footnotes
transaction	HRTX	Common Stock	Options Exercise		+12,500	+10%		135,066	06 Jun 2025	Direct	F1

Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Underlying Class	Amount	Exercise Price	Ownership	Footnotes
transaction	HRTX	Restricted Stock Units	Options Exercise	$0	-12,500	-33%	$0.000000	25,000	06 Jun 2025	Common Stock	12,500	$0.000000	Direct	F2

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id	Content
F1	Each restricted stock unit represents a contingent right to receive one share of common stock.
F2	The restricted stock units vest in four equal annual installments beginning one year after the date of grant, subject to the Reporting Person's continued service to the Issuer through the vesting date.