| Name | Relationship | Address | Signature | Signature date | CIK |
|---|---|---|---|---|---|
| Rubin Steven D | Executive VP-Administration, Director | OPKO HEALTH, INC., 4400 BISCAYNE BLVD., MIAMI | Steven D. Rubin | 29 May 2025 | 0001381874 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Underlying Class | Amount | Exercise Price | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | OPK | Stock Option (Right to Buy) | Award | $0 | +437,500 | $0.000000 | 437,500 | 27 May 2025 | Common Stock | 437,500 | $1.31 | Direct | F1 |
| Id | Content |
|---|---|
| F1 | This option will vest in four equal annual installments beginning May 27, 2026. |