Thermo Fisher Scientific Inc. - Dec 8, 2021 Form 3/A - Amendment Insider Report for Science 37 Holdings, Inc. (SNCE)

Role: 10%+ Owner
Signature: Thermo Fisher Scientific Powder US Holdings Corp. By: /s/ Maura A. Spellman, Title: Treasurer
Stock symbol: SNCE
Transactions as of: Dec 8, 2021
Transactions value $: $0
Form type: 3/A - Amendment
Date filed: 12/27/2021, 04:07 PM
Date Of Original Report: Dec 20, 2021
Next filing: Mar 14, 2024

Transactions Table

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Ownership	Footnotes
holding	SNCE	Common Stock						17.4M	Dec 8, 2021	See footnote	F1, F2

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id	Content
F1	These shares of common stock, par value $0.0001 per share, of Science 37 Holdings, Inc. are held of record by Pharmaceutical Product Development, LLC ("Pharma LLC"). Wildcat Acquisition Holdings (UK) Limited ("Wildcat") is the sole member of Pharma LLC; Jaguar Holding Company II ("Jaguar II") is the sole shareholder of Wildcat; Jaguar Holding Company I, LLC ("Jaguar I") is the sole shareholder of Jaguar II; Eagle Holding Company II, LLC ("Eagle II") is the sole member of Jaguar I; PPD, Inc. ("PPD") is the sole member of Eagle II; Thermo Fisher Scientific Powder US Holdings Corp. ("Powder Holdings") is the sole shareholder of PPD; and Thermo Fisher Scientific Inc. is the sole shareholder of Powder Holdings. By virtue of such relationships, each of the reporting persons may be deemed to have beneficial ownership over such shares of common stock.
F2	This report on Form 3 is jointly filed by the reporting persons. Each of the reporting persons disclaims beneficial ownership of the securities reported herein for purposes of Rule 16a-1(a) under the Securities Exchange Act of 1934, as amended (the "Exchange Act"), except to the extent of its pecuniary interest therein. Disclosure of the information required by this Form was made by Pharma LLC, Wildcat, Jaguar II, Jaguar I, Eagle II and PPD pursuant to PPD, Inc.'s Form 3 filed on October 18, 2021 and Form 3/A filed on November 8, 2021.

Content

These shares of common stock, par value $0.0001 per share, of Science 37 Holdings, Inc. are held of record by Pharmaceutical Product Development, LLC ("Pharma LLC"). Wildcat Acquisition Holdings (UK) Limited ("Wildcat") is the sole member of Pharma LLC; Jaguar Holding Company II ("Jaguar II") is the sole shareholder of Wildcat; Jaguar Holding Company I, LLC ("Jaguar I") is the sole shareholder of Jaguar II; Eagle Holding Company II, LLC ("Eagle II") is the sole member of Jaguar I; PPD, Inc. ("PPD") is the sole member of Eagle II; Thermo Fisher Scientific Powder US Holdings Corp. ("Powder Holdings") is the sole shareholder of PPD; and Thermo Fisher Scientific Inc. is the sole shareholder of Powder Holdings. By virtue of such relationships, each of the reporting persons may be deemed to have beneficial ownership over such shares of common stock.

This report on Form 3 is jointly filed by the reporting persons. Each of the reporting persons disclaims beneficial ownership of the securities reported herein for purposes of Rule 16a-1(a) under the Securities Exchange Act of 1934, as amended (the "Exchange Act"), except to the extent of its pecuniary interest therein. Disclosure of the information required by this Form was made by Pharma LLC, Wildcat, Jaguar II, Jaguar I, Eagle II and PPD pursuant to PPD, Inc.'s Form 3 filed on October 18, 2021 and Form 3/A filed on November 8, 2021.

Remarks:

This Form 3/A amends and restates the original Form 3 filed by the reporting persons on December 20, 2021. This amendment is being filed to include Thermo Fisher Scientific Powder US Holdings Corp. as a reporting person.