Pioneering Medicines 02, LLC - 02 Mar 2026 Form 3 Insider Report for Generate Biomedicines, Inc. (GENB)

Role: 10%+ Owner
Signature: Pioneering Medicines 02, LLC, By: /s/ Charles R. Carelli, Jr., Manager
Issuer symbol: GENB
Transactions as of: 02 Mar 2026
Net transactions value: $0
Form type: 3
Filing time: 12 Mar 2026, 17:00:03 UTC
SEC: View on sec.gov

Reporting Owners (1)

Name	Relationship	Address	Signature	Signature date	CIK
Pioneering Medicines 02, LLC	10%+ Owner	55 CAMBRIDGE PARKWAY,, SUITE 800E, CAMBRIDGE	Pioneering Medicines 02, LLC, By: /s/ Charles R. Carelli, Jr., Manager	12 Mar 2026	0002117576

Transactions Table

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Ownership	Footnotes
holding	GENB	Common Stock						1,562,500	02 Mar 2026	By Pioneering Medicines 02, LLC	F1

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id	Content
F1	Securities held by Pioneering Medicines 02, LLC ("PM02"). Charles R. Carelli, Jr., Chief Financial Officer of Flagship Pioneering, LLC ("Flagship Pioneering"), is the sole manager of PM02, and Flagship Pioneering Fund VII, L.P. ("Flagship Fund VII") is its majority equity holder. Flagship Pioneering Fund VII General Partner LLC ("Flagship Fund VII GP") is the general partner of Flagship Fund VII. Flagship Pioneering is the manager of Flagship Fund VII GP. Noubar B. Afeyan, Ph.D. is the ultimate control person of Flagship Pioneering. The Reporting Person disclaims beneficial ownership of such shares except to the extent of its pecuniary interest therein, if any.

Content

Securities held by Pioneering Medicines 02, LLC ("PM02"). Charles R. Carelli, Jr., Chief Financial Officer of Flagship Pioneering, LLC ("Flagship Pioneering"), is the sole manager of PM02, and Flagship Pioneering Fund VII, L.P. ("Flagship Fund VII") is its majority equity holder. Flagship Pioneering Fund VII General Partner LLC ("Flagship Fund VII GP") is the general partner of Flagship Fund VII. Flagship Pioneering is the manager of Flagship Fund VII GP. Noubar B. Afeyan, Ph.D. is the ultimate control person of Flagship Pioneering. The Reporting Person disclaims beneficial ownership of such shares except to the extent of its pecuniary interest therein, if any.