Dana Aftab - 24 Feb 2026 Form 4 Insider Report for EXELIXIS, INC. (EXEL)

Role: EVP, Research and Development
Signature: /s/ Nina Ayer, Attorney in Fact
Issuer symbol: EXEL
Transactions as of: 24 Feb 2026
Net transactions value: -$2,132,351
Form type: 4
Filing time: 26 Feb 2026, 18:41:37 UTC
Previous filing: 23 Feb 2026
Next filing: 02 Mar 2026
SEC: View on sec.gov

Reporting Owners (1)

Name	Relationship	Address	Signature	Signature date	CIK
Aftab Dana	EVP, Research and Development	C/O EXELIXIS, INC., 1851 HARBOR BAY PARKWAY, ALAMEDA	/s/ Nina Ayer, Attorney in Fact	26 Feb 2026	0001959132

Transactions Table

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Ownership	Footnotes
transaction	EXEL	Common Stock	Sale	$2,132,351	-47,918	-7.2%	$44.50	616,106	24 Feb 2026	Direct	F1
holding	EXEL	Common Stock						5,835	24 Feb 2026	By 401(k)	F2

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id	Content
F1	Includes 414,043 shares of Exelixis, Inc. common stock ("Common Stock") that will be issued to the Reporting Person upon vesting of restricted stock units ("RSUs") and PSUs granted to the Reporting Person on March 31, 2025 ("One-Time Award PSUs"). Each RSU is the economic equivalent of one share of Common Stock and each One-Time Award PSU represents a contingent right to receive one share of Common Stock.
F2	Represents shares of Common Stock under the Exelixis, Inc. 401(k) Plan, pursuant to a plan statement dated as of February 23, 2026.

Content

Includes 414,043 shares of Exelixis, Inc. common stock ("Common Stock") that will be issued to the Reporting Person upon vesting of restricted stock units ("RSUs") and PSUs granted to the Reporting Person on March 31, 2025 ("One-Time Award PSUs"). Each RSU is the economic equivalent of one share of Common Stock and each One-Time Award PSU represents a contingent right to receive one share of Common Stock.

Represents shares of Common Stock under the Exelixis, Inc. 401(k) Plan, pursuant to a plan statement dated as of February 23, 2026.