Stelios Papadopoulos - 12 Nov 2025 Form 4 Insider Report for EXELIXIS, INC. (EXEL)

Role: Director
Signature: /s/ Nina Ayer, Attorney in Fact
Issuer symbol: EXEL
Transactions as of: 12 Nov 2025
Net transactions value: -$4,355,000
Form type: 4
Filing time: 13 Nov 2025, 19:12:53 UTC
Previous filing: 27 Jun 2025
Next filing: 02 Mar 2026
SEC: View on sec.gov

Reporting Owners (1)

Name	Relationship	Address	Signature	Signature date	CIK
PAPADOPOULOS STELIOS	Director	C/O EXELIXIS, INC., 1851 HARBOR BAY PARKWAY, ALAMEDA	/s/ Nina Ayer, Attorney in Fact	13 Nov 2025	0001202098

Transactions Table

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Ownership	Footnotes
transaction	EXEL	Common Stock	Sale	$4,355,000	-100,000	-7.8%	$43.55	1,189,228	12 Nov 2025	Direct	F1, F2

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id	Content
F1	Represents the weighted average sales price. The shares were sold in multiple transactions at prices ranging from $43.55 to $43.58. Reporting Person undertakes to provide Exelixis, Inc., any security holder of Exelixis, Inc., or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnote 1 to this Form 4.
F2	Includes 9,812 shares of Exelixis, Inc. common stock ("Common Stock") that will be issued to the Reporting Person upon vesting of restricted stock units ("RSUs"). Each RSU is the economic equivalent of one share of Common Stock.

Content

Represents the weighted average sales price. The shares were sold in multiple transactions at prices ranging from $43.55 to $43.58. Reporting Person undertakes to provide Exelixis, Inc., any security holder of Exelixis, Inc., or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnote 1 to this Form 4.

Includes 9,812 shares of Exelixis, Inc. common stock ("Common Stock") that will be issued to the Reporting Person upon vesting of restricted stock units ("RSUs"). Each RSU is the economic equivalent of one share of Common Stock.