| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Underlying Class | Amount | Exercise Price | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | ZYME | Pre-Funded Warrants | Purchase | $50M | +5.09M | $9.83 | 5.09M | Dec 26, 2023 | Common Stock | 5.09M | $0.00 | See note | F1, F2, F3, F4, F5 |
| Id | Content |
|---|---|
| F1 | The reporting persons are EcoR1 Capital, LLC ("EcoR1"), Oleg Nodelman and EcoR1 Capital Fund Qualified, L.P. ("Qualified Fund"). EcoR1 is the general partner and investment adviser of private funds, including Qualified Fund (the "Funds"). Mr. Nodelman is the manager and controlling owner of EcoR1. EcoR1 is filing this Form 4 for itself, Mr. Nodelman and Qualified Fund. The filers are filing this Form 4 jointly, but not as a group, and each expressly disclaims membership in a group within the meaning of Rule 13d-5(b) under the Securities Exchange Act of 1934. The Funds hold these securities directly for the benefit of their investors. EcoR1 may be deemed to indirectly beneficially own them as the investment adviser to the Funds. Mr. Nodelman may be deemed to indirectly beneficially own them as the control person of EcoR1. The filers disclaim beneficial ownership of the securities except to the extent of their respective pecuniary interests therein. |
| F2 | Qualified Fund purchased 4,818,462 of the pre-funded warrants reported in this transaction. |
| F3 | The pre-funded warrants do not have an expiration date. |
| F4 | Each pre-funded warrant will be exercisable to purchase one share of Common Stock, except that the pre-funded warrants cannot be exercised if, after giving effect or immediately prior to such exercise, the reporting person, together with its affiliates and any other persons whose beneficial ownership of shares of Common Stock would be aggregated with the reporting person for purposes of Section 13(d) of the Securities Exchange Act of 1934 would beneficially own more than 19.99% of the total number of issued and outstanding shares of Common Stock or voting power of the issuer following such exercise. |
| F5 | After this transaction, Qualified Fund owned 4,818,462 of the pre-funded warrants. |