Ashwath Jayagopal - 16 Mar 2026 Form 4 Insider Report for Opus Genetics, Inc. (IRD)

Role: Chief Scientific & Dev. Ofc.
Signature: /s/ Amy Rabourn, by Power of Attorney
Issuer symbol: IRD
Transactions as of: 16 Mar 2026
Net transactions value: -$19,046
Form type: 4
Filing time: 18 Mar 2026, 16:09:24 UTC
Previous filing: 17 Feb 2026
SEC: View on sec.gov

Reporting Owners (1)

Name	Relationship	Address	Signature	Signature date	CIK
Jayagopal Ashwath	Chief Scientific & Dev. Ofc.	C/O OPUS GENETICS, INC., 8 DAVIS DRIVE, SUITE 220, DURHAM	/s/ Amy Rabourn, by Power of Attorney	18 Mar 2026	0002008983

Transactions Table

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Ownership	Footnotes
transaction	IRD	Common Stock	Sale	$19,046	-3,719	-0.71%	$5.12	516,775	16 Mar 2026	Direct	F1, F2

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id	Content
F1	The shares reported on this line were sold automatically on behalf of the Reporting Person, as required by the Company to satisfy tax withholding obligations that arose in connection with a vesting and settlement event from a restricted stock units award. This transaction does not represent a discretionary trade by the Reporting Person.
F2	The price in column 4 represents the weighted average price. The shares were sold in multiple transactions at prices ranging from $5.11 to $5.1301, inclusive. The Reporting Person undertakes to provide the issuer, any securityholder of the issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

Content

The shares reported on this line were sold automatically on behalf of the Reporting Person, as required by the Company to satisfy tax withholding obligations that arose in connection with a vesting and settlement event from a restricted stock units award. This transaction does not represent a discretionary trade by the Reporting Person.

The price in column 4 represents the weighted average price. The shares were sold in multiple transactions at prices ranging from $5.11 to $5.1301, inclusive. The Reporting Person undertakes to provide the issuer, any securityholder of the issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.