Mansoor Raza Mirza - 01 Oct 2025 Form 4 Insider Report for Acrivon Therapeutics, Inc. (ACRV)

Role: Chief Medical Officer
Signature: /s/ Adam D. Levy, Attorney-in-Fact
Issuer symbol: ACRV
Transactions as of: 01 Oct 2025
Net transactions value: $0
Form type: 4
Filing time: 03 Oct 2025, 16:28:11 UTC
Previous filing: 05 Sep 2025
Next filing: 06 Oct 2025
SEC: View on sec.gov

Reporting Owners (1)

Name	Relationship	Address	Signature	Signature date	CIK
Mirza Mansoor Raza	Chief Medical Officer	C/O ACRIVON THERAPEUTICS, INC., 480 ARSENAL WAY, SUITE 100, WATERTOWN	/s/ Adam D. Levy, Attorney-in-Fact	03 Oct 2025	0001588389

Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Underlying Class	Amount	Exercise Price	Ownership	Footnotes
transaction	ACRV	Stock Option (Right to Buy)	Award	$0	+225,000		$0.000000	225,000	01 Oct 2025	Common Stock	225,000	$1.81	Direct	F1

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id	Content
F1	Twenty-five percent (25%) of the shares subject to the option vest on November 1, 2026, and the remaining shares subject to the option vest in 36 substantially equal monthly installments thereafter, in each case subject to the Reporting Person's continuous service through each vesting date.