Kylie O'Keefe - 25 Feb 2026 Form 3 Insider Report for uniQure N.V. (QURE)

Role: Chief Customer & Strat Officer
Signature: /s/ Christian Klemt, Attorney-in-Fact
Issuer symbol: QURE
Transactions as of: 25 Feb 2026
Net transactions value: $0
Form type: 3
Filing time: 09 Mar 2026, 20:57:50 UTC
Next filing: 09 Mar 2026
SEC: View on sec.gov

Reporting Owners (1)

Name	Relationship	Address	Signature	Signature date	CIK
O'Keefe Kylie	Chief Customer & Strat Officer	C/O UNIQURE N.V., PAASHEUVELWEG 25A, AMSTERDAM	/s/ Christian Klemt, Attorney-in-Fact	09 Mar 2026	0002118100

Transactions Table

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Ownership	Footnotes
holding	QURE	Ordinary Shares						105,000	25 Feb 2026	Direct	F1

Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Underlying Class	Amount	Exercise Price	Ownership	Footnotes
holding	QURE	Stock Option (Right to Buy)							25 Feb 2026	Ordinary Shares	180,000	$16.22	Direct	F2

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id	Content
F1	Represents restricted share units ("RSUs") granted to the Reporting Person on June 11, 2025. Each RSU represents the contingent right to receive one Ordinary Share. The RSUs vest in three equal annual installments, with the first vesting date to occur on the first anniversary of the date of grant, subject to the Reporting Person's continued relationship with the Issuer through each such vesting date.
F2	The option was granted to the Reporting Person on June 11, 2025 and vests over four years beginning on the first anniversary of the date of grant, with 25% of the shares underlying the option vesting on the first anniversary of the date of grant, and 6.25% of the shares underlying the option vesting quarterly thereafter until June 11, 2029, subject to the Reporting Person's continued relationship with the Issuer through each such vesting date.

Content

Represents restricted share units ("RSUs") granted to the Reporting Person on June 11, 2025. Each RSU represents the contingent right to receive one Ordinary Share. The RSUs vest in three equal annual installments, with the first vesting date to occur on the first anniversary of the date of grant, subject to the Reporting Person's continued relationship with the Issuer through each such vesting date.

The option was granted to the Reporting Person on June 11, 2025 and vests over four years beginning on the first anniversary of the date of grant, with 25% of the shares underlying the option vesting on the first anniversary of the date of grant, and 6.25% of the shares underlying the option vesting quarterly thereafter until June 11, 2029, subject to the Reporting Person's continued relationship with the Issuer through each such vesting date.

Remarks:

Exhibit List: Exhibit 24 - Power of Attorney