Matrix Capital Management Company, LP - 15 Dec 2025 Form 4 Insider Report for Zentalis Pharmaceuticals, Inc. (ZNTL)

Role: 10%+ Owner
Signature: Matrix Capital Management Company, LP, by: /s/ Gregory A. Brown, General Counsel, Chief Compliance Officer
Issuer symbol: ZNTL
Transactions as of: 15 Dec 2025
Net transactions value: -$9,975,000
Form type: 4
Filing time: 15 Dec 2025, 17:24:17 UTC
Previous filing: 09 Nov 2023
SEC: View on sec.gov

Reporting Owners (2)

Name	Relationship	Address	Signature	Signature date	CIK
Matrix Capital Management Company, LP	10%+ Owner	1000 WINTER STREET, SUITE 4500, WALTHAM	Matrix Capital Management Company, LP, by: /s/ Gregory A. Brown, General Counsel, Chief Compliance Officer	15 Dec 2025	0001410830
GOEL DAVID E.	10%+ Owner	C/O MATRIX CAPITAL MANAGEMENT CO., LP, 1000 WINTER STREET, SUITE 4500, WALTHAM	/s/ David E. Goel	15 Dec 2025	0001548144

Transactions Table

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Ownership	Footnotes
transaction	ZNTL	Common Stock, par value $0.001 per share	Sale	$9,975,000	-7,500,000	-54%	$1.33	6,459,973	15 Dec 2025	See footnotes	F1, F2

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Matrix Capital Management Company, LP is no longer subject to Section 16 filing requirements. Form 4 or Form 5 obligations may continue.

Explanation of Responses:

Id	Content
F1	The securities reported herein are held by Matrix Capital Management Master Fund, LP (the "Matrix Fund"). Matrix Capital Management Company, LP (the "Investment Manager"), a Delaware limited partnership, is the investment advisor to the Matrix Fund. Mr. David E. Goel ("Mr. Goel", and together with the Investment Manager, the "Reporting Persons"), serves as the Managing General Partner of the Investment Manager.
F2	The filing of this statement shall not be deemed an admission that either of the Reporting Persons is the beneficial owner of the securities reported herein for purposes of Section 16 of the Securities Act of 1934, as amended, or otherwise. Each of the Reporting Persons expressly disclaims beneficial ownership of the securities reported herein except to the extent of its or his pecuniary interest therein.

Content

The securities reported herein are held by Matrix Capital Management Master Fund, LP (the "Matrix Fund"). Matrix Capital Management Company, LP (the "Investment Manager"), a Delaware limited partnership, is the investment advisor to the Matrix Fund. Mr. David E. Goel ("Mr. Goel", and together with the Investment Manager, the "Reporting Persons"), serves as the Managing General Partner of the Investment Manager.

The filing of this statement shall not be deemed an admission that either of the Reporting Persons is the beneficial owner of the securities reported herein for purposes of Section 16 of the Securities Act of 1934, as amended, or otherwise. Each of the Reporting Persons expressly disclaims beneficial ownership of the securities reported herein except to the extent of its or his pecuniary interest therein.