Amit Sachdev - Aug 10, 2023 Form 4 Insider Report for VERTEX PHARMACEUTICALS INC / MA (VRTX)

Role: EVP, Chief Patient Officer
Signature: /s/ Christiana Stevenson, Attorney-in-Fact
Stock symbol: VRTX
Transactions as of: Aug 10, 2023
Transactions value $: -$3,510,850
Form type: 4
Date filed: 8/14/2023, 04:05 PM
Previous filing: Mar 3, 2023
Next filing: Nov 17, 2023

Transactions Table

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Ownership	Footnotes
transaction	VRTX	Common Stock	Sale	-$3.51M	-10K	-14.57%	$350.00	58.8K	Aug 10, 2023	Direct	F1
holding	VRTX	Common Stock						882	Aug 10, 2023	401(k)
holding	VRTX	Common Stock						6.57K	Aug 10, 2023	Held in Trust

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Buy Plan / Sale Plan: These are also open market purchases/sales of shares, but in this case the transaction is part of a trading plan. Rule 10b5-1 allows insiders to setup a trading plan to buy/sell stocks over a certain period of time. Since the purchases/sales are predetermined, this protects the insiders from violating insider trading law.

Transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c).

Explanation of Responses:

Id	Content
F1	Transaction made pursuant to Mr. Sachdev's company approved trading plan under Rule 10b5-1, which was entered into on 05/09/2023.