| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | VRTX | Common Stock | Options Exercise | $1,022,250 | +6,571 | +11% | $155.57 | 67,451 | 15 Aug 2022 | Direct | |
| transaction | VRTX | Common Stock | Sale | $376,576 | -1,254 | -1.9% | $300.30 | 66,197 | 15 Aug 2022 | Direct | F1, F2, F3 |
| transaction | VRTX | Common Stock | Sale | $1,279,430 | -4,242 | -6.4% | $301.61 | 61,955 | 15 Aug 2022 | Direct | F1, F2, F4 |
| transaction | VRTX | Common Stock | Sale | $121,020 | -400 | -0.65% | $302.55 | 61,555 | 15 Aug 2022 | Direct | F1, F2, F5 |
| transaction | VRTX | Common Stock | Sale | $710,541 | -2,339 | -3.8% | $303.78 | 59,216 | 15 Aug 2022 | Direct | F1, F2, F6 |
| transaction | VRTX | Common Stock | Sale | $2,129,643 | -6,990 | -12% | $304.67 | 52,226 | 15 Aug 2022 | Direct | F1, F2, F7 |
| transaction | VRTX | Common Stock | Sale | $2,121,780 | -6,948 | -13% | $305.38 | 45,278 | 15 Aug 2022 | Direct | F1, F2, F8 |
| holding | VRTX | Common Stock | 140 | 15 Aug 2022 | 401(k) |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Underlying Class | Amount | Exercise Price | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | VRTX | Stock Option (Right to Buy) | Options Exercise | $0 | -6,571 | -100% | $0.000000* | 0 | 15 Aug 2022 | Common Stock | 6,571 | $155.57 | Direct | F9 |
| Id | Content |
|---|---|
| F1 | Transaction made pursuant to Mr. Arbuckle's company approved trading plan under Rule 10b5-1. |
| F2 | Mr. Arbuckle undertakes to provide (upon request by the SEC staff, the Issuer or a security holder of the Issuer) full information regarding the number of shares sold at each separate price. |
| F3 | Open market sales reported on this line occurred at a weighted average price of $300.30 (range $300.00 to $300.73). |
| F4 | Open market sales reported on this line occurred at a weighted average price of $301.61 (range $301.09 to $302.01). |
| F5 | Open market sales reported on this line occurred at a weighted average price of $302.55 (range $302.13 to $302.90). |
| F6 | Open market sales reported on this line occurred at a weighted average price of $303.78 (range $303.13 to $304.09). |
| F7 | Open market sales reported on this line occurred at a weighted average price of $304.67 (range $304.13 to $305.12). |
| F8 | Open market sales reported on this line occurred at a weighted average price of $305.38 (range $305.13 to $305.83). |
| F9 | Fully vested. |