| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | VRTX | Common Stock | Options Exercise | $163,080 | +2,000 | +107% | $81.54 | 3,875 | 04 Apr 2022 | Direct | |
| transaction | VRTX | Common Stock | Sale | $26,583 | -100 | -2.6% | $265.83 | 3,775 | 04 Apr 2022 | Direct | F1 |
| transaction | VRTX | Common Stock | Sale | $245,050 | -917 | -24% | $267.23 | 2,858 | 04 Apr 2022 | Direct | F1, F2, F3 |
| transaction | VRTX | Common Stock | Sale | $263,798 | -983 | -34% | $268.36 | 1,875 | 04 Apr 2022 | Direct | F1, F2, F4 |
| transaction | VRTX | Common Stock | Options Exercise | $163,080 | +2,000 | +107% | $81.54 | 3,875 | 05 Apr 2022 | Direct | |
| transaction | VRTX | Common Stock | Sale | $4,561 | -17 | -0.44% | $268.30 | 3,858 | 05 Apr 2022 | Direct | F1 |
| transaction | VRTX | Common Stock | Sale | $90,197 | -334 | -8.7% | $270.05 | 3,524 | 05 Apr 2022 | Direct | F1, F2, F5 |
| transaction | VRTX | Common Stock | Sale | $132,707 | -488 | -14% | $271.94 | 3,036 | 05 Apr 2022 | Direct | F1, F2, F6 |
| transaction | VRTX | Common Stock | Sale | $163,560 | -600 | -20% | $272.60 | 2,436 | 05 Apr 2022 | Direct | F1, F2, F7 |
| transaction | VRTX | Common Stock | Sale | $27,350 | -100 | -4.1% | $273.50 | 2,336 | 05 Apr 2022 | Direct | F1 |
| transaction | VRTX | Common Stock | Sale | $126,618 | -461 | -20% | $274.66 | 1,875 | 05 Apr 2022 | Direct | F1, F2, F8 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Underlying Class | Amount | Exercise Price | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | VRTX | Stock Option (Right to Buy) | Options Exercise | $163,080 | -2,000 | -10% | $81.54 | 18,000 | 04 Apr 2022 | Common Stock | 2,000 | $81.54 | Direct | F9 |
| transaction | VRTX | Stock Option (Right to Buy) | Options Exercise | $163,080 | -2,000 | -11% | $81.54 | 16,000 | 05 Apr 2022 | Common Stock | 2,000 | $81.54 | Direct | F9 |
| Id | Content |
|---|---|
| F1 | Transaction made pursuant to Mr. Lee's company approved trading plan under Rule 10b5-1. |
| F2 | Mr. Lee undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price. |
| F3 | Open market sales reported on this line occurred at a weighted average price of $267.23 (range $266.85 to $267.79). |
| F4 | Open market sales reported on this line occurred at a weighted average price of $268.36 (range $267.97 to $268.81). |
| F5 | Open market sales reported on this line occurred at a weighted average price of $270.05 (range $269.79 to $270.64). |
| F6 | Open market sales reported on this line occurred at a weighted average price of $271.94 (range $271.35 to $272.27). |
| F7 | Open market sales reported on this line occurred at a weighted average price of $272.60 (range $272.36 to $273.34). |
| F8 | Open market sales reported on this line occurred at a weighted average price of $274.66 (range $274.63 to $274.68). |
| F9 | Fully vested. |
Exhibit List: Exhibit 24 - Power of Attorney