David Altshuler - Feb 24, 2022 Form 4 Insider Report for VERTEX PHARMACEUTICALS INC / MA (VRTX)

Role: EVP, Global Research and CSO
Signature: /s/ Sabrina Yohai, Attorney-in-Fact
Stock symbol: VRTX
Transactions as of: Feb 24, 2022
Transactions value $: -$3,124,808
Form type: 4
Date filed: 2/28/2022, 04:18 PM
Previous filing: Feb 22, 2022
Next filing: Jul 21, 2022
SEC: View on sec.gov

Transactions Table

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Ownership	Footnotes
transaction	VRTX	Common Stock	Tax liability	-$1.38M	-6.04K	-12.15%	$227.86	43.6K	Feb 24, 2022	Direct
transaction	VRTX	Common Stock	Sale	-$239K	-1.04K	-2.38%	$229.41	42.6K	Feb 25, 2022	Direct	F1, F2, F3
transaction	VRTX	Common Stock	Sale	-$735K	-3.19K	-7.48%	$230.62	39.4K	Feb 25, 2022	Direct	F1, F3, F4
transaction	VRTX	Common Stock	Sale	-$645K	-2.78K	-7.06%	$231.64	36.6K	Feb 25, 2022	Direct	F1, F3, F5
transaction	VRTX	Common Stock	Sale	-$130K	-560	-1.53%	$232.68	36.1K	Feb 25, 2022	Direct	F1, F3, F6

Showing 1 to 5 of 5 entries

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id	Content
F1	Transaction made pursuant to Mr. Altshuler's company approved trading plan under Rule 10b5-1.
F2	Open market sales reported on this line occurred at a weighted average price of $229.41 (range $228.91 to $229.81).
F3	Mr. Altshuler undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.
F4	Open market sales reported on this line occurred at a weighted average price of $230.62 (range $230.07 to $231.05).
F5	Open market sales reported on this line occurred at a weighted average price of $231.64 (range $231.08 to $232.07).
F6	Open market sales reported on this line occurred at a weighted average price of $232.68 (range $232.43 to $232.87).