Jeffery Kutok - Feb 2, 2022 Form 4 Insider Report for Epizyme, Inc. (EPZM)

Role: Chief Scientific Officer
Signature: /s/ John Weidenbruch, attorney-in-fact
Stock symbol: EPZM
Transactions as of: Feb 2, 2022
Transactions value $: -$3,502
Form type: 4
Date filed: 2/4/2022, 03:15 PM
Previous filing: Aug 18, 2021
Next filing: Mar 21, 2022

Transactions Table

Type	Sym	Class	Transaction	Value $	Shares	Change %	* Price $	Shares After	Date	Ownership	Footnotes
transaction	EPZM	Common Stock, par value $0.0001	Sale	-$3.5K	-2.56K	-2.56%	$1.37	97.3K	Feb 2, 2022	Direct	F1

* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id	Content
F1	Represents shares of Common Stock automatically sold by the reporting person to satisfy tax withholding obligations in connection with the vesting of restricted stock units granted under the Company's 2013 Stock Incentive Plan on February 1, 2021. The automatic sale of the reporting person's shares of Common Stock is provided for in a restricted stock unit agreement constituting a "binding contract" consistent with the affirmative defense to liability under Rule 10b5-1 and the sale does not represent a discretionary trade by the reporting person.

Content

Represents shares of Common Stock automatically sold by the reporting person to satisfy tax withholding obligations in connection with the vesting of restricted stock units granted under the Company's 2013 Stock Incentive Plan on February 1, 2021. The automatic sale of the reporting person's shares of Common Stock is provided for in a restricted stock unit agreement constituting a "binding contract" consistent with the affirmative defense to liability under Rule 10b5-1 and the sale does not represent a discretionary trade by the reporting person.